Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNA7 | P36544 | 9/20 | 0.79 |
| ▸ | GUSB | P08236 | 4/20 | 0.66 |
| ▸ | MGAM | O43451 | 1/20 | 0.65 |
| ▸ | GAA | P10253 | 1/20 | 0.65 |
| ▸ | SI | P14410 | 1/20 | 0.65 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.65 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.62 |
| ▸ | TYR | P14679 | 1/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7196345 | 1.00 | CHRNA7 (0.79) | CHRNA7GUSBMGAMGAASI | |
| SCHEMBL7194724 | 0.89 | CHRNA7 (0.64) | CHRNA7GUSBNR1H4 | |
| SCHEMBL7194727 | 0.89 | CHRNA7 (0.64) | CHRNA7GUSBNR1H4 | |
| SCHEMBL7198540 | 0.88 | CHRNA7 (0.77) | CHRNA7GUSBGAA | |
| SCHEMBL7198542 | 0.88 | CHRNA7 (0.77) | CHRNA7GUSBGAA | |
| SCHEMBL5426768 | 0.88 | CHRNA7 (1.00) | CHRNA7GUSBNR1H4TYR | |
| SCHEMBL5426767 | 0.88 | CHRNA7 (1.00) | CHRNA7GUSBNR1H4TYR | |
| SCHEMBL19236264 | 0.88 | CHRNA7 (1.00) | CHRNA7GUSBNR1H4TYR | |
| SCHEMBL634060 | 0.82 | CHRNA7 (1.00) | CHRNA7GUSB | |
| SCHEMBL634059 | 0.82 | CHRNA7 (1.00) | CHRNA7GUSB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030065039-A1 | Biologically active 1,3-bis-aromatic-prop-2-en-1-ones, 1,3-bis-aromatic-propan-1-ones, and 1,3-bis-aromatic-prop-2-yn-1-ones | STATENS SERUM INSTITUTE (DK) | 2003-04-03 | — | — | US | claimed |
| EP-0996432-A2 | BIOLOGICALLY ACTIVE 1,3-BIS-AROMATIC-PROP-2-EN-1-ONES, 1,3-BIS-AROMATIC-PROPAN-1-ONES, AND 1,3-BIS-AROMATIC-PROP-2-YN-1-ONES | STATENS SERUMINSTITUT (DK) | 2000-05-03 | — | — | EP | claimed |
| WO-1999000114-A2 | BIOLOGICALLY ACTIVE 1,3-BIS-AROMATIC-PROP-2-EN-1-ONES, 1,3-BIS-AROMATIC-PROPAN-1-ONES, AND 1,3-BIS-AROMATIC-PROP-2-YN-1-ONES | STATENS SERUM INSTITUT (DK) | 1999-01-07 | — | — | WO | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030065039-A1 | Biologically active 1,3-bis-aromatic-prop-2-en-1-ones, 1,3-bis-aromatic-propan-1-ones, and 1,3-bis-aromatic-prop-2-yn-1-ones | AKR1C3, AKR1C1, AKR1A1 | CHRNA7 4280/4885GUSB 1352/4885MGAM 4188/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.