SCHEMBL7196403

SCHEMBL7196403

CCOP(=O)(CC(C)=O)OCC.O=CCCP(=O)(O)O

nearest known ligand 0.45

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
PPARD Q03181 2/20 0.39
AOX1 Q06278 1/20 0.39
BTN3A1 O00481 1/20 0.36
TSHR P16473 1/20 0.35
CYP2D6 P10635 1/20 0.33
CYP2C9 P11712 1/20 0.33
CYP2C19 P33261 1/20 0.33
FNTA P49354 1/20 0.31
FNTB P49356 1/20 0.31
PGGT1B P53609 1/20 0.31
MAPT P10636 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL246813 0.80 TSHR (0.52) PPARDTSHRMAPT
SCHEMBL2382808 0.74 PPARD (0.54) PPARDAOX1BTN3A1TSHRCYP2C9
Methyl Alcohol SCHEMBL28029809 0.72 BTN3A1 (0.48) BTN3A1
SCHEMBL3718509 0.72
Methane SCHEMBL28455124 0.70
SCHEMBL28593773 0.70 AOX1 (0.46) PPARDAOX1BTN3A1TSHR
SCHEMBL8351172 0.68 PPARD (0.62) PPARDTSHR
SCHEMBL8643733 0.68 TSHR (0.57) PPARDTSHRMAPT
Formaldehyde SCHEMBL8386730 0.68 TYMS (0.43) BTN3A1
SCHEMBL2382263 0.67 PPARD (0.50) PPARDAOX1TSHRMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6589766-B1 Use to catalyze ketone-ketone, ketone-aldehyde, aldehyde-ketone, and aldehyde-aldehyde intermolecular aldol reactions, and in some cases to catalyze their subsequent dehydration to yield aldol condensation products THE SCRIPPS RESEARCH INSTITUTE 2003-07-08 US disclosed