Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.52 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | CASP1 | P29466 | 12/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.33 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28834303 | 0.94 | TDP1 (0.43) | TDP1TSHRPKMSMN1; SMN2CASP1 | |
| SCHEMBL2446951 | 0.81 | TDP1 (0.40) | TDP1TSHRPKMSMN1; SMN2CASP1 | |
| SCHEMBL7196449 | 0.80 | TDP1 (0.44) | TDP1TSHRPKMSMN1; SMN2CASP1 | |
| SCHEMBL5368563 | 0.79 | TDP1 (0.43) | TDP1TSHRPKMSMN1; SMN2CASP1 | |
| SCHEMBL5368556 | 0.78 | TDP1 (0.40) | TDP1TSHRPKMSMN1; SMN2CASP1 | |
| SCHEMBL11298080 | 0.78 | TDP1 (0.40) | TDP1TSHRPKMSMN1; SMN2CASP1 | |
| SCHEMBL829459 | 0.77 | SMN1; SMN2 (0.43) | TDP1TSHRPKMSMN1; SMN2CASP1 | |
| SCHEMBL16574651 | 0.76 | TDP1 (0.49) | TDP1TSHRPKMSMN1; SMN2CASP1 | |
| SCHEMBL12477531 | 0.76 | TDP1 (0.41) | TDP1TSHRPKMSMN1; SMN2CASP1 | |
| SCHEMBL2201794 | 0.76 | GRIK1 (0.47) | TDP1TSHRPKMSMN1; SMN2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003010566-A2 | PLASTIC LENS MATERIAL, PLASTIC LENS COMPOSITION, PLASTIC LENS OBTAINED BY CURING THE COMPOSITION AND PROCESS FOR PRODUCING THE PLASTIC LENS | SHOWA DENKO K. K. (JP) | 2003-02-06 | — | — | WO | disclosed |