SCHEMBL7196546

SCHEMBL7196546

O=C(O)C=CC(C=CC(=O)O)(C=CC(=O)O)C=CC(=O)O

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 4/20 0.53
TP53 P04637 1/20 0.53
EGLN1 Q9GZT9 1/20 0.53
EGLN3 Q9H6Z9 1/20 0.53
LMNA P02545 2/20 0.41
TDP1 Q9NUW8 3/20 0.36
GABRR1 P24046 2/20 0.36
GABRR2 P28476 2/20 0.36
BLM P54132 2/20 0.36
GABRR3 A8MPY1 1/20 0.36
APEX1 P27695 1/20 0.36
NPSR1 Q6W5P4 1/20 0.36
HCAR2 Q8TDS4 4/20 0.35
GABRP O00591 2/20 0.33
GABRD O14764 2/20 0.33
GABRA1 P14867 2/20 0.33
GABRB1 P18505 2/20 0.33
GABRG2 P18507 2/20 0.33
GABRB3 P28472 2/20 0.33
GABRA5 P31644 2/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Maleic Acid SCHEMBL8466867 0.76 TSHR (0.90) TSHRTP53EGLN1EGLN3LMNA
Maleic Acid SCHEMBL459171 0.76
SCHEMBL2589072 0.76 TSHR (0.50) TSHRTP53EGLN1EGLN3LMNA
SCHEMBL13464136 0.73
SCHEMBL21457 0.73
Maleic Acid SCHEMBL3742398 0.72
Maleic Acid SCHEMBL29014432 0.72
Fumaric Acid SCHEMBL615 0.71
Fumaric Acid SCHEMBL2046433 0.71 TSHR (1.00) TSHRTP53EGLN1EGLN3LMNA
Maleic Acid SCHEMBL613 0.71

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6593052-B2 Binder resin, a colorant, a sulfur-containing resin, and a wax; the binder resin containing a hybrid resin component containing a vinyl type polymer unit and a polyester unit CANON KABUSHIKI KAISHA (JP) 2003-07-15 US disclosed
US-20020045120-A1 Toner, image forming method and process cartridge CANON KABUSHIKI KAISHA (JP) 2002-04-18 US disclosed