Known targets — ChEMBL curated mechanism
ACEADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2BTKCACNA1CCACNA1DCACNA1FCACNA1SCCR5CPT1BCPT2DPP4DRD1DRD2EGFRERBB2ERBB4HRH1HRH3HTR1AHTR2AHTR2BHTR2CHTR4JAK1JAK2JAK3MPLMTORPPIK3CAPIK3CBPIK3CDPIK3CGPIK3R1PIK3R2PIK3R3PIK3R5PPARGSLC6A2SLC6A3SLC6A4SMOTYK2pol
The experimentally established mechanism targets of Maleic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Fumaric Acid SCHEMBL672934 | 0.95 | — | — | |
| Fumaric Acid SCHEMBL672180 | 0.95 | — | — | |
| Maleic Acid SCHEMBL8466867 | 0.95 | TSHR (0.90) | — | |
| Maleic Acid SCHEMBL459171 | 0.95 | — | — | |
| Maleic Acid SCHEMBL672179 | 0.95 | — | — | |
| Maleic Acid SCHEMBL29014432 | 0.91 | — | — | |
| Maleic Acid SCHEMBL27967963 | 0.91 | TSHR (0.82) | — | |
| Fumaric Acid SCHEMBL14717098 | 0.91 | TSHR (0.82) | — | |
| Fumaric Acid SCHEMBL3998225 | 0.91 | — | — | |
| Fumaric Acid SCHEMBL615 | 0.91 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7829127-B2 | Fortification of syrup with calcium and other minerals and vitamins | THE HERSHEY COMPANY (US) | 2010-11-09 | — | — | US | claimed |
| WO-2009105272-A1 | METHOD FOR PREPARING PRECOOKED FROZEN SHELLFISH IN PACKAGING SUITABLE FOR COOKING | PREMIER SEAFOOD, L.L.C. (US) | 2009-08-27 | — | — | WO | claimed |
| US-20090148579-A1 | Method for preparing precooked frozen shellfish in packaging suitable for cooking | PREMIER SEAFOOD, L.L.C. | 2009-06-11 | — | — | US | claimed |
| WO-2009048588-A1 | METHOD FOR PREPARING PRECOOKED FROZEN SHELLFISH HAVING EXTENDED SHELF LIFE | PREMIER SEAFOOD, L.L.C. (US) | 2009-04-16 | — | — | WO | claimed |
| US-20090092726-A1 | Method for preparing precooked frozen shellfish having extended shelf life | PREMIER SEAFOOD, L.L.C. | 2009-04-09 | — | — | US | claimed |
| WO-2009023262-A1 | CALCIUM FORTIFIED CREAMED HONEY | HONEYCAL, L.L.C. (US) | 2009-02-19 | — | — | WO | claimed |
| US-20090047388-A1 | CALCIUM FORTIFIED CREAMED HONEY | HONEYCAL, L.L.C. | 2009-02-19 | — | — | US | claimed |
| US-20060216376-A1 | Fortification of syrup with calcium and other minerals and vitamins | HERSHEY FOODS CORPORATION (US) | 2006-09-28 | — | — | US | claimed |
| US-7829127-B2 | Fortification of syrup with calcium and other minerals and vitamins | THE HERSHEY COMPANY (US) | 2010-11-09 | — | — | US | disclosed |
| WO-2009105272-A1 | METHOD FOR PREPARING PRECOOKED FROZEN SHELLFISH IN PACKAGING SUITABLE FOR COOKING | PREMIER SEAFOOD, L.L.C. (US) | 2009-08-27 | — | — | WO | disclosed |
| US-20090148579-A1 | Method for preparing precooked frozen shellfish in packaging suitable for cooking | PREMIER SEAFOOD, L.L.C. | 2009-06-11 | — | — | US | disclosed |
| WO-2009048588-A1 | METHOD FOR PREPARING PRECOOKED FROZEN SHELLFISH HAVING EXTENDED SHELF LIFE | PREMIER SEAFOOD, L.L.C. (US) | 2009-04-16 | — | — | WO | disclosed |
| US-20090092726-A1 | Method for preparing precooked frozen shellfish having extended shelf life | PREMIER SEAFOOD, L.L.C. | 2009-04-09 | — | — | US | disclosed |
| WO-2009023262-A1 | CALCIUM FORTIFIED CREAMED HONEY | HONEYCAL, L.L.C. (US) | 2009-02-19 | — | — | WO | disclosed |
| US-20090047388-A1 | CALCIUM FORTIFIED CREAMED HONEY | HONEYCAL, L.L.C. | 2009-02-19 | — | — | US | disclosed |
| US-20060216376-A1 | Fortification of syrup with calcium and other minerals and vitamins | HERSHEY FOODS CORPORATION (US) | 2006-09-28 | — | — | US | disclosed |
| EP-0680957-B1 | PROCESS FOR PRODUCING cis-EPOXYSUCCINIC ACID SALT | MITSUBISHI CHEM CORP (JP) | 2000-03-29 | — | — | EP | disclosed |