Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 20/20 | 0.44 |
| ▸ | PPARD | Q03181 | 20/20 | 0.44 |
| ▸ | PPARA | Q07869 | 17/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7193985 | 0.94 | PPARG (0.43) | PPARGPPARDPPARA | |
| SCHEMBL7194097 | 0.92 | PPARG (0.37) | PPARGPPARDPPARA | |
| SCHEMBL7187738 | 0.89 | PPARG (0.48) | PPARGPPARDPPARA | |
| SCHEMBL7195026 | 0.87 | PPARG (0.44) | PPARGPPARDPPARA | |
| SCHEMBL7199234 | 0.85 | PPARG (0.36) | PPARGPPARDPPARA | |
| SCHEMBL7189553 | 0.85 | PPARG (0.44) | PPARGPPARDPPARA | |
| SCHEMBL7198834 | 0.85 | PPARG (0.46) | PPARGPPARDPPARA | |
| SCHEMBL7189684 | 0.85 | PPARG (0.42) | PPARGPPARDPPARA | |
| SCHEMBL7190583 | 0.83 | PPARG (0.47) | PPARGPPARDPPARA | |
| SCHEMBL7194007 | 0.83 | PPARG (0.46) | PPARGPPARDPPARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030065039-A1 | Biologically active 1,3-bis-aromatic-prop-2-en-1-ones, 1,3-bis-aromatic-propan-1-ones, and 1,3-bis-aromatic-prop-2-yn-1-ones | STATENS SERUM INSTITUTE (DK) | 2003-04-03 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030065039-A1 | Biologically active 1,3-bis-aromatic-prop-2-en-1-ones, 1,3-bis-aromatic-propan-1-ones, and 1,3-bis-aromatic-prop-2-yn-1-ones | AKR1C3, AKR1C1, AKR1A1 | PPARG 659/4885PPARD 405/4885PPARA 600/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.