SCHEMBL7196751

SCHEMBL7196751

COC(=O)c1ccc(OCCOCCO)cc1

nearest known ligand 0.77

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 6/20 0.77
RAB9A P51151 3/20 0.69
TDP1 Q9NUW8 1/20 0.58
L3MBTL1 Q9Y468 1/20 0.58
SMN1; SMN2 Q16637 4/20 0.55
KDM4E B2RXH2 3/20 0.55
ALDH1A1 P00352 3/20 0.55
LMNA P02545 3/20 0.55
HPGD P15428 1/20 0.55
CA1 P00915 1/20 0.53
CA2 P00918 1/20 0.53
APP P05067 4/20 0.52
NPC1 O15118 2/20 0.51
MEN1 O00255 2/20 0.49
KMT2A Q03164 2/20 0.49
RARB P10826 1/20 0.49
USP2 O75604 1/20 0.49
CYP3A4 P08684 1/20 0.49
MAPK1 P28482 1/20 0.49
CASP1 P29466 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30325159 1.00 MAPT (0.77) MAPTRAB9ATDP1L3MBTL1SMN1; SMN2
SCHEMBL8916699 1.00 MAPT (0.77) MAPTRAB9ATDP1L3MBTL1SMN1; SMN2
SCHEMBL14274445 0.93 MAPT (0.89) MAPTRAB9ATDP1L3MBTL1SMN1; SMN2
SCHEMBL64651 0.90 MAPT (0.82) MAPTRAB9ATDP1L3MBTL1SMN1; SMN2
SCHEMBL22495352 0.89 MAPT (0.75) MAPTRAB9ATDP1L3MBTL1SMN1; SMN2
SCHEMBL21063817 0.89 MAPT (0.80) MAPTRAB9ATDP1L3MBTL1SMN1; SMN2
SCHEMBL1951546 0.88 MAPT (1.00) MAPTRAB9ATDP1L3MBTL1SMN1; SMN2
SCHEMBL4815928 0.87 MAPT (0.77) MAPTRAB9ATDP1L3MBTL1SMN1; SMN2
SCHEMBL13252834 0.86 MAPT (0.75) MAPTRAB9ATDP1L3MBTL1SMN1; SMN2
SCHEMBL26627769 0.85 MAPT (0.80) MAPTRAB9ATDP1L3MBTL1SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-108440251-B Method for photo/nickel concerted catalysis of monoarylation diol 陕西师范大学 2021-01-01 CN disclosed
US-7759126-B2 Real-time linear detection probes: sensitive 5′-minor groove binder-containing probes for amplification (or PCR) analysis ELITECH HOLDING B.V. (NL) 2010-07-20 US disclosed
US-20080293586-A1 FLUORESCENT PROBES FOR DNA DETECTION BY HYBRIDIZATION WITH IMPROVED SENSITIVITY AND LOW BACKGROUND EPOCH BIOSCIENCES, INC. (US) 2008-11-27 US disclosed
US-7381818-B2 Fluorescent probes containing 5′-minor groove binder, fluorophore and quenching moieties and methods of use thereof EPOCH BIOSCIENCES, INC. (US) 2008-06-03 US disclosed
EP-0922726-B1 BIAXIALLY ORIENTED POLYETHYLENE NAPHTHALATE COPOLYMER FILM TEIJIN LTD (JP) 2003-03-26 EP disclosed
US-6048627-A PHOTOGRAPHY BASE FILM, FILMS FOR X-RAYS AND PHOTOENGRAVING TEIJIN LIMITED (JP) 2000-04-11 US disclosed
EP-0922726-A1 BIAXIALLY ORIENTED POLYETHYLENE NAPHTHALATE COPOLYMER FILM TEIJIN LIMITED (JP) 1999-06-16 EP disclosed
US-5656197-A Ferroelectric liquid crystal NATIONAL SCIENCE COUNCIL (TW) 1997-08-12 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080293586-A1 FLUORESCENT PROBES FOR DNA DETECTION BY HYBRIDIZATION WITH IMPROVED SENSITIVITY AND LOW BACKGROUND SSBP1, DDB1, DNA2 MAPT 3770/4885RAB9A 4755/4885TDP1 237/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.