Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.77 |
| ▸ | RAB9A | P51151 | 3/20 | 0.69 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.58 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.55 |
| ▸ | LMNA | P02545 | 3/20 | 0.55 |
| ▸ | HPGD | P15428 | 1/20 | 0.55 |
| ▸ | CA1 | P00915 | 1/20 | 0.53 |
| ▸ | CA2 | P00918 | 1/20 | 0.53 |
| ▸ | APP | P05067 | 4/20 | 0.52 |
| ▸ | NPC1 | O15118 | 2/20 | 0.51 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | RARB | P10826 | 1/20 | 0.49 |
| ▸ | USP2 | O75604 | 1/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | CASP1 | P29466 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30325159 | 1.00 | MAPT (0.77) | MAPTRAB9ATDP1L3MBTL1SMN1; SMN2 | |
| SCHEMBL7196751 | 1.00 | MAPT (0.77) | MAPTRAB9ATDP1L3MBTL1SMN1; SMN2 | |
| SCHEMBL14274445 | 0.93 | MAPT (0.89) | MAPTRAB9ATDP1L3MBTL1SMN1; SMN2 | |
| SCHEMBL64651 | 0.90 | MAPT (0.82) | MAPTRAB9ATDP1L3MBTL1SMN1; SMN2 | |
| SCHEMBL22495352 | 0.89 | MAPT (0.75) | MAPTRAB9ATDP1L3MBTL1SMN1; SMN2 | |
| SCHEMBL21063817 | 0.89 | MAPT (0.80) | MAPTRAB9ATDP1L3MBTL1SMN1; SMN2 | |
| SCHEMBL1951546 | 0.88 | MAPT (1.00) | MAPTRAB9ATDP1L3MBTL1SMN1; SMN2 | |
| SCHEMBL4815928 | 0.87 | MAPT (0.77) | MAPTRAB9ATDP1L3MBTL1SMN1; SMN2 | |
| SCHEMBL13252834 | 0.86 | MAPT (0.75) | MAPTRAB9ATDP1L3MBTL1SMN1; SMN2 | |
| SCHEMBL26627769 | 0.85 | MAPT (0.80) | MAPTRAB9ATDP1L3MBTL1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250136619-A1 | HETEROBIFUNCTIONAL COMPOUNDS AND THEIR USE IN TREATING DISEASE | HALDA THERAPEUTICS OPCO, INC. | 2025-05-01 | — | — | US | disclosed |
| WO-2023059581-A1 | HETEROBIFUNCTIONAL COMPOUNDS AND THEIR USE IN TREATING DISEASE | HALDA THERAPEUTICS OPCO, INC. (US) | 2023-04-13 | — | — | WO | disclosed |
| US-5656197-A | Ferroelectric liquid crystal | NATIONAL SCIENCE COUNCIL (TW) | 1997-08-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250136619-A1 | HETEROBIFUNCTIONAL COMPOUNDS AND THEIR USE IN TREATING DISEASE | CDK9, AURKB, AURKC | MAPT 912/4885RAB9A 156/4885TDP1 1578/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.