SCHEMBL7196841

SCHEMBL7196841

CC(=O)N(S)c1ccc2ccccc2c1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 5/20 0.43
KMT2A Q03164 5/20 0.43
POLB P06746 2/20 0.43
ESR1 P03372 1/20 0.42
ESR2 Q92731 1/20 0.42
CES2 O00748 1/20 0.42
CES1 P23141 1/20 0.42
SMN1; SMN2 Q16637 2/20 0.41
ALDH1A1 P00352 2/20 0.41
KDM4E B2RXH2 2/20 0.41
HPGD P15428 1/20 0.41
MTNR1A P48039 1/20 0.41
MTNR1B P49286 1/20 0.41
L3MBTL1 Q9Y468 2/20 0.41
HTT P42858 1/20 0.41
NPSR1 Q6W5P4 1/20 0.41
CYP1A2 P05177 1/20 0.40
CYP2C19 P33261 1/20 0.40
HIF1A Q16665 1/20 0.40
NPC1 O15118 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL651823 0.81 ESR1 (0.42) MEN1KMT2APOLBESR1ESR2
SCHEMBL1176872 0.81 ESR1 (0.49) MEN1KMT2APOLBESR1ESR2
SCHEMBL27277472 0.81 CRHBP (0.47) MEN1KMT2APOLBESR1ESR2
SCHEMBL1137614 0.79 PDK2 (0.47) MEN1KMT2APOLBESR1ESR2
SCHEMBL27662354 0.78 MEN1 (0.43) MEN1KMT2APOLBESR1ESR2
SCHEMBL2038478 0.78 ESR1 (0.46) MEN1KMT2APOLBESR1ESR2
SCHEMBL28749398 0.78 HTT (0.44) MEN1KMT2APOLBESR1ESR2
SCHEMBL1509980 0.77 KMT2A (0.38) KMT2APOLBSMN1; SMN2ALDH1A1KDM4E
SCHEMBL5398870 0.76 CRHBP (0.47) MEN1KMT2APOLBESR1ESR2
SCHEMBL14921002 0.76 NPSR1 (0.46) MEN1KMT2APOLBCES2CES1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4320209-A Amide nucleating agents for butene-1 polymer compositions SHELL OIL COMPANY (US) 1982-03-16 US claimed
CN-101912975-B Method for preparing ultrahigh monodisperse nickel sol by using novel protective agent UNIV NINGBO 2013-10-23 CN disclosed
CN-101912975-A Method for preparing ultrahigh monodisperse nickel sol by using novel protective agent UNIV NINGBO 2010-12-15 CN disclosed
EP-0943672-B1 Hot melt adhesive composition KRATON POLYMERS RES BV (NL) 2003-10-29 EP disclosed
US-6211272-B1 HOT MELT ADHESIVES WITH POLYBUTENE AND TACKIFIER RESINS SHELL OIL COMPANY 2001-04-03 US disclosed
EP-0943672-A1 Hot melt adhesive composition SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) 1999-09-22 EP disclosed
EP-0310393-B1 Olefin polymer compositions for use with water systems SHELL OIL CO (US) 1995-01-18 EP disclosed
EP-0250076-B1 POLYOLEFIN COMPOSITIONS FOR USE WITH HOT WATER SYSTEMS SHELL OIL COMPANY (US) 1992-07-29 EP disclosed
US-4937138-A TACKIFYING RESIN, NUCLEATING AGENT, STABILIZER, PLASTICIZER AND WAX SHELL OIL COMPANY (US) 1990-06-26 US disclosed
EP-0331410-A2 Hot melt adhesive comprising a butene-1 polymer SHELL OIL COMPANY (US) 1989-09-06 EP disclosed
EP-0310393-A2 Olefin polymer compositions for use with water systems SHELL OIL COMPANY (US) 1989-04-05 EP disclosed
US-4812500-A Polyolefin compositions for water pipes and for wire and cable coatings SHELL OIL COMPANY (US) 1989-03-14 US disclosed
US-4746692-A RESISTANCE TO HOT CHLORINATED WATER SHELL OIL COMPANY (US) 1988-05-24 US disclosed
EP-0250076-A2 Polyolefin compositions for use with hot water systems SHELL OIL COMPANY (US) 1987-12-23 EP disclosed
US-4579900-A CONTAINING POLYBUTYLENE, ANTIOXIDANTS, NUCLEATING AGENT, AND FILLERS SHELL OIL COMPANY (US) 1986-04-01 US disclosed
US-4576983-A Polymeric composition useful for hot water pipe service SHELL OIL COMPANY (US) 1986-03-18 US disclosed
US-4359544-A COMPRISING STEARAMIDE AND HIGH DENSITY POLYETHYLENE SHELL OIL COMPANY (US) 1982-11-16 US disclosed
US-4320209-A Amide nucleating agents for butene-1 polymer compositions SHELL OIL COMPANY (US) 1982-03-16 US disclosed
US-4320209-A Amide nucleating agents for butene-1 polymer compositions SHELL OIL COMPANY (US) 1982-03-16 US disclosed
US-4148815-A Amino-thiol nickel and cobalt solvent extraction KENNECOTT COPPER CORPORATION (US) 1979-04-10 US disclosed