Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 1/20 | 0.73 |
| ▸ | ESR1 | P03372 | 2/20 | 0.57 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.57 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.57 |
| ▸ | TACR2 | P21452 | 2/20 | 0.57 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.57 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.57 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.57 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.57 |
| ▸ | CASP2 | P42575 | 1/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.57 |
| ▸ | LMNA | P02545 | 1/20 | 0.57 |
| ▸ | SHBG | P04278 | 1/20 | 0.57 |
| ▸ | TP53 | P04637 | 1/20 | 0.57 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.57 |
| ▸ | HSPD1 | P10809 | 1/20 | 0.57 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.57 |
| ▸ | HTR2C | P28335 | 1/20 | 0.57 |
| ▸ | HSPE1 | P61604 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7888252 | 1.00 | HPGD (0.73) | HPGDESR1ADRA2AADORA3TACR2 | |
| SCHEMBL8387272 | 1.00 | HPGD (0.73) | HPGDESR1ADRA2AADORA3TACR2 | |
| SCHEMBL7201453 | 1.00 | HPGD (0.73) | HPGDESR1ADRA2AADORA3TACR2 | |
| SCHEMBL423695 | 0.94 | HPGD (0.68) | HPGDHSD17B10KDM4ELMNATRPV1 | |
| SCHEMBL11367962 | 0.94 | HPGD (0.82) | HPGDHSD17B10CASP2TRPV1MEN1 | |
| SCHEMBL8646182 | 0.92 | HPGD (0.63) | HPGDESR1ADRA2AADORA3TACR2 | |
| SCHEMBL7194125 | 0.91 | ESR1 (0.63) | HPGDESR1ADRA2AADORA3TACR2 | |
| SCHEMBL7193335 | 0.91 | ESR1 (0.63) | HPGDESR1ADRA2AADORA3TACR2 | |
| SCHEMBL8366228 | 0.91 | HSD17B10 (0.69) | HPGDHSD17B10KDM4ELMNATP53 | |
| SCHEMBL7193607 | 0.91 | ESR1 (0.63) | HPGDESR1ADRA2AADORA3TACR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6596669-B1 | Comprising a support and two reversible heat-sensitive recording layers having different colors formed on the same side of the support, comprising colorless electron-donative dye precursor and an electron-accepting compound | MITSUBISHI PAPER MILLS LIMITED (JP) | 2003-07-22 | — | — | US | disclosed |
| US-6004899-A | SURFACE TREATED WITH SILANE, TITANATE, AND/OR ALUMINUM COUPLING AGENT; PIGMENT; ERASIBILITY | MITSUBISHI PAPER MILLS LIMITED (JP) | 1999-12-21 | — | — | US | disclosed |
| US-4427649-A | A CORTICOSTEROID HAVING AN 11-HYDROXY GROUP AND A 21-LIPOPHILIC ESTER GROUP | IMPERIAL CHEMICAL INDUSTRIES LIMITED (GB) | 1984-01-24 | — | — | US | disclosed |