SCHEMBL8646182

SCHEMBL8646182

CCCCCCCCCCSCCCCCCCCCCCNC(=O)CCc1ccc(O)cc1

nearest known ligand 0.63

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HPGD P15428 1/20 0.63
TRPV1 Q8NER1 3/20 0.50
HSD17B10 Q99714 2/20 0.50
MEN1 O00255 1/20 0.50
MAPT P10636 1/20 0.50
KMT2A Q03164 1/20 0.50
POLB P06746 1/20 0.49
ESR1 P03372 3/20 0.49
ADRA2A P08913 2/20 0.49
ADORA3 P0DMS8 2/20 0.49
TACR2 P21452 2/20 0.49
SLC6A2 P23975 2/20 0.49
SLC6A4 P31645 2/20 0.49
SLC6A3 Q01959 2/20 0.49
CASP2 P42575 1/20 0.49
KDM4E B2RXH2 1/20 0.49
ALDH1A1 P00352 1/20 0.49
LMNA P02545 1/20 0.49
SHBG P04278 1/20 0.49
TP53 P04637 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7201453 0.92 HPGD (0.73) HPGDTRPV1HSD17B10MEN1MAPT
SCHEMBL7197012 0.92 HPGD (0.73) HPGDTRPV1HSD17B10MEN1MAPT
SCHEMBL8387272 0.92 HPGD (0.73) HPGDTRPV1HSD17B10MEN1MAPT
SCHEMBL7888252 0.92 HPGD (0.73) HPGDTRPV1HSD17B10MEN1MAPT
SCHEMBL423695 0.86 HPGD (0.68) HPGDTRPV1HSD17B10MEN1MAPT
SCHEMBL11367962 0.86 HPGD (0.82) HPGDTRPV1HSD17B10MEN1MAPT
SCHEMBL8621969 0.86 ESR1 (0.51) TRPV1HSD17B10MEN1MAPTKMT2A
SCHEMBL8623300 0.86 ESR1 (0.50) HPGDTRPV1HSD17B10ESR1ADRA2A
SCHEMBL7194125 0.84 ESR1 (0.63) HPGDTRPV1HSD17B10MEN1MAPT
SCHEMBL7193335 0.84 ESR1 (0.63) HPGDTRPV1HSD17B10MEN1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0648612-B1 Reversible heat-sensitive recording material MITSUBISHI PAPER MILLS LTD (JP) 1998-06-10 EP disclosed
US-5498772-A SUBSTRATE WITH HEAT SENSITIVE LAYER AND OPTICAL RECORDING LAYER MITSUBISHI PAPER MILLS LIMITED (JP) 1996-03-12 US disclosed
EP-0648612-A1 Reversible heat-sensitive recording material MITSUBISHI PAPER MILLS, LTD. (JP) 1995-04-19 EP disclosed