Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | CES2 | O00748 | 2/20 | 0.43 |
| ▸ | CES1 | P23141 | 2/20 | 0.43 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | CNR2 | P34972 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7193418 | 0.88 | MEN1 (0.47) | CES2CES1AKR1B1TP53MEN1 | |
| SCHEMBL4920838 | 0.86 | MEN1 (0.54) | CES2CES1TP53MEN1KMT2A | |
| SCHEMBL22431869 | 0.85 | CES2 (0.44) | L3MBTL1CYP3A4CYP2C19CES2CES1 | |
| Water SCHEMBL9769518 | 0.84 | MEN1 (0.53) | CES2CES1TP53MEN1KMT2A | |
| SCHEMBL2313487 | 0.82 | CES1 (0.46) | L3MBTL1CES2CES1AKR1B1TP53 | |
| SCHEMBL2241627 | 0.81 | CES1 (0.55) | L3MBTL1CES2CES1AKR1B1MEN1 | |
| SCHEMBL11645900 | 0.80 | TDP1 (0.46) | L3MBTL1CES2CES1AKR1B1MEN1 | |
| SCHEMBL24434862 | 0.79 | MAPT (0.39) | CYP3A4CYP2C19 | |
| Ammonia Solution, Strong SCHEMBL574785 | 0.79 | CES1 (0.52) | L3MBTL1CES2CES1AKR1B1MEN1 | |
| Ammonia Solution, Strong SCHEMBL27465072 | 0.79 | CES1 (0.52) | L3MBTL1CES2CES1AKR1B1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0915913-A1 | HIGH INTERNAL PHASE EMULSIONS AND POROUS MATERIALS PREPARED THEREFROM | THE DOW CHEMICAL COMPANY (US) | 1999-05-19 | — | — | EP | claimed |
| WO-1998051713-A1 | HIGH INTERNAL PHASE EMULSIONS AND POROUS MATERIALS PREPARED THEREFROM | THE DOW CHEMICAL COMPANY (US) | 1998-11-19 | — | — | WO | claimed |
| US-6534595-B2 | Blend of thermosetting resin, decomposable resin and solvent | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2003-03-18 | — | — | US | disclosed |
| US-20010038887-A1 | Coating solution for forming porous organic film | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2001-11-08 | — | — | US | disclosed |
| US-5559143-A | Serotonin 5HT1A agonistic method | MERRELL PHARMACEUTICALS INC. (US) | 1996-09-24 | — | — | US | disclosed |
| US-5387604-A | 1,4 benzodioxin derivatives and their use as serotonin 5HT1A agonists | MERRELL DOW PHARMACEUTICALS INC. (US) | 1995-02-07 | — | — | US | disclosed |
| US-5189179-A | SEROTONIN 5HT1A AGONISTS | MERRELL DOW PHARMACEUTICALS INC. (US) | 1993-02-23 | — | — | US | disclosed |
| EP-0478954-A1 | Serotonin 5HT1A and 5HT1D antagonists | MERRELL PHARMACEUTICALS INC. (US) | 1992-04-08 | — | — | EP | disclosed |