SCHEMBL7197819

SCHEMBL7197819

CCCCCCCCCCCCN(C(=O)O)c1ccc(-c2ccc(O)cc2)cc1

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LTB4R2 Q9NPC1 5/20 0.54
NPC1 O15118 1/20 0.51
JAK2 O60674 1/20 0.51
RAB9A P51151 1/20 0.51
PAX8 Q06710 1/20 0.51
PTGES O14684 2/20 0.44
ALOX5 P09917 2/20 0.44
HSD17B3 P37058 6/20 0.44
ESR1 P03372 2/20 0.41
ADRA2A P08913 2/20 0.41
ADORA3 P0DMS8 2/20 0.41
TACR2 P21452 2/20 0.41
SLC6A2 P23975 2/20 0.41
SLC6A4 P31645 2/20 0.41
SLC6A3 Q01959 2/20 0.41
KDM4E B2RXH2 1/20 0.41
ALDH1A1 P00352 1/20 0.41
LMNA P02545 1/20 0.41
SHBG P04278 1/20 0.41
TP53 P04637 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7195860 1.00 LTB4R2 (0.54) LTB4R2NPC1JAK2RAB9APAX8
SCHEMBL8391735 0.87 NPC1 (0.48) LTB4R2NPC1JAK2RAB9APAX8
SCHEMBL7201621 0.87 LTA4H (0.51) LTB4R2NPC1JAK2RAB9APAX8
SCHEMBL9000287 0.87 NPC1 (0.48) LTB4R2NPC1JAK2RAB9APAX8
SCHEMBL7200496 0.87 LTA4H (0.51) LTB4R2NPC1JAK2RAB9APAX8
SCHEMBL7195885 0.87 LTA4H (0.51) LTB4R2NPC1JAK2RAB9APAX8
SCHEMBL7201373 0.87 LTA4H (0.51) LTB4R2NPC1JAK2RAB9APAX8
SCHEMBL7200510 0.87 LTB4R2 (0.47) LTB4R2NPC1JAK2RAB9APAX8
SCHEMBL7197123 0.84 LTB4R2 (0.45) LTB4R2NPC1JAK2RAB9APAX8
SCHEMBL8390888 0.83 NPC1 (0.51) LTB4R2NPC1JAK2RAB9APAX8

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6596669-B1 Comprising a support and two reversible heat-sensitive recording layers having different colors formed on the same side of the support, comprising colorless electron-donative dye precursor and an electron-accepting compound MITSUBISHI PAPER MILLS LIMITED (JP) 2003-07-22 US disclosed
EP-0648612-B1 Reversible heat-sensitive recording material MITSUBISHI PAPER MILLS LTD (JP) 1998-06-10 EP disclosed
US-5498772-A SUBSTRATE WITH HEAT SENSITIVE LAYER AND OPTICAL RECORDING LAYER MITSUBISHI PAPER MILLS LIMITED (JP) 1996-03-12 US disclosed
EP-0648612-A1 Reversible heat-sensitive recording material MITSUBISHI PAPER MILLS, LTD. (JP) 1995-04-19 EP disclosed