Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.93 |
| ▸ | CYP3A4 | P08684 | 5/20 | 0.93 |
| ▸ | HPGD | P15428 | 3/20 | 0.93 |
| ▸ | TSHR | P16473 | 3/20 | 0.93 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.93 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.93 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.65 |
| ▸ | KEAP1 | Q14145 | 2/20 | 0.63 |
| ▸ | IDO1 | P14902 | 3/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.52 |
| ▸ | MEN1 | O00255 | 2/20 | 0.52 |
| ▸ | MAPT | P10636 | 2/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.52 |
| ▸ | TTR | P02766 | 1/20 | 0.52 |
| ▸ | PARP1 | P09874 | 1/20 | 0.52 |
| ▸ | RECQL | P46063 | 1/20 | 0.52 |
| ▸ | USP2 | O75604 | 1/20 | 0.52 |
| ▸ | TDP2 | O95551 | 1/20 | 0.52 |
| ▸ | POLB | P06746 | 1/20 | 0.52 |
| ▸ | TDO2 | P48775 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27912581 | 0.96 | ALDH1A1 (1.00) | ALDH1A1CYP3A4HPGDTSHRHSD17B10 | |
| SCHEMBL48843 | 0.96 | ALDH1A1 (1.00) | ALDH1A1CYP3A4HPGDTSHRHSD17B10 | |
| SCHEMBL29365003 | 0.96 | ALDH1A1 (1.00) | ALDH1A1CYP3A4HPGDTSHRHSD17B10 | |
| Fluoride SCHEMBL27639109 | 0.93 | ALDH1A1 (0.93) | ALDH1A1CYP3A4HPGDTSHRHSD17B10 | |
| Hydrochloric Acid SCHEMBL28166221 | 0.93 | CYP3A4 (0.93) | ALDH1A1CYP3A4HPGDTSHRHSD17B10 | |
| SCHEMBL335367 | 0.93 | ALDH1A1 (0.93) | ALDH1A1CYP3A4HPGDTSHRHSD17B10 | |
| Hydrochloric Acid SCHEMBL8641121 | 0.93 | CYP3A4 (0.93) | ALDH1A1CYP3A4HPGDTSHRHSD17B10 | |
| SCHEMBL21854609 | 0.90 | ALDH1A1 (0.87) | ALDH1A1CYP3A4HPGDTSHRHSD17B10 | |
| SCHEMBL16107418 | 0.90 | ALDH1A1 (0.87) | ALDH1A1CYP3A4HPGDTSHRHSD17B10 | |
| SCHEMBL14876644 | 0.90 | ALDH1A1 (0.87) | ALDH1A1CYP3A4HPGDTSHRHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2897933-B1 | METHOD OF PRODUCING DIISOCYANATES BY PHOSGENATION OF DIAMINE SUSPENSIONS | COVESTRO DEUTSCHLAND AG (DE) | 2017-06-07 | — | — | EP | disclosed |
| US-9272988-B2 | Method for producing diisocyanates by phosgenating diamine suspensions | COVESTRO DEUTSCHLAND AG (DE) | 2016-03-01 | — | — | US | disclosed |
| US-20150246873-A1 | METHOD FOR PRODUCING DIISOCYANATES BY PHOSGENATING DIAMINE SUSPENSIONS | BAYER MATERIALSCIENCE AG (DE) | 2015-09-03 | — | — | US | disclosed |
| US-6538158-B2 | Process for preparing 1,4-diaminonaphthalene and/or 1,5-diaminoNaphthalene | BAYER AKTIENGESELLSCHAFT (DE) | 2003-03-25 | — | — | US | disclosed |
| US-20020198408-A1 | Process for preparing 1,4-diaminonaphthalene and/or 1,5-diaminonaphthalene | COVESTRO DEUTSCHLAND AG (DE) | 2002-12-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150246873-A1 | METHOD FOR PRODUCING DIISOCYANATES BY PHOSGENATING DIAMINE SUSPENSIONS | DDT, DUS2, SAT1 | ALDH1A1 1852/4885CYP3A4 1512/4885HPGD 453/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.