SCHEMBL7197848

SCHEMBL7197848

CCCC[SiH](CCCC)[Hf](Cl)(Cl)(c1cccc2c1Cc1ccccc1-2)c1cccc2c1Cc1ccccc1-2

nearest known ligand 0.39

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
PNMT P11086 1/20 0.39
NPC1 O15118 2/20 0.35
RAB9A P51151 2/20 0.35
SIGMAR1 Q99720 2/20 0.32
HTR7 P34969 3/20 0.31
HTR2B P41595 1/20 0.31
DRD2 P14416 1/20 0.30
DRD4 P21917 1/20 0.30
DRD3 P35462 1/20 0.30
HTR1A P08908 2/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7579397 0.92 PNMT (0.41) PNMTNPC1RAB9AHTR7HTR2B
SCHEMBL7575737 0.88 PNMT (0.38) PNMTNPC1RAB9ASIGMAR1HTR7
SCHEMBL7580011 0.86 PNMT (0.43) PNMTNPC1RAB9AHTR7HTR2B
SCHEMBL7577029 0.84 PNMT (0.37) PNMTNPC1RAB9ASIGMAR1
SCHEMBL7579887 0.84 PNMT (0.37) PNMTNPC1RAB9ASIGMAR1
SCHEMBL7197705 0.79 PNMT (0.42) PNMTNPC1RAB9AHTR7HTR2B
SCHEMBL6805929 0.73 PNMT (0.35) PNMTNPC1RAB9A
Hydrochloric Acid SCHEMBL7197849 0.73 PNMT (0.41) PNMTNPC1RAB9ASIGMAR1HTR7
SCHEMBL7577350 0.72 PNMT (0.43) PNMTNPC1RAB9AHTR7HTR2B
Hydrochloric Acid SCHEMBL7575740 0.72 PNMT (0.40) PNMTNPC1RAB9ASIGMAR1HTR7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0729984-B1 Processfor the preparation of atactic copolymers of propylene with ethylene BASELL POLYOLEFINE GMBH (DE) 2003-07-30 EP disclosed
EP-0729968-B1 Bridged bis-fluorenyl metallocenes, process for the preparation thereof and use thereof in catalysts for the polymerization of olefins BASELL POLYOLEFINE GMBH (DE) 2002-09-25 EP disclosed
US-6365764-B1 METALLOCENE COMPOUNDS HAVING TWO FLUORENYL LIGANDS BRIDGED WITH A SINGLE SILICON OR GERMANIUM ATOM BASELL TECHNOLOGY COMPANY BV (NL) 2002-04-02 US disclosed
US-6180733-B1 OLEFIN POLYMERIZATION USING CATALYST COMPRISING THE PRODUCT OF REACTION BETWEEN A GROUP 4 OR 5 METALLOCENE COMPOUND AND AN ALUMOXANE, OPTIONALLY WITH ORGANOALUMINUM OR COMPOUND ABLE TO GIVE A METALLOCENE ALKYL CATION; ATACTIC POLYPROPYLENE MONTELL TECHNOLOGY COMPANY BV (NL) 2001-01-30 US disclosed
US-6111046-A POLYMERIZATION IN THE PRESENCE OF A CATALYST BASED ON A METALLOCENE COMPOUND THAT HAS TWO BRIDGED FLUORENYL LIGANDS; LOW GLASS TRANSITION TEMPERATURES MONTELL TECHNOLOGY COMPANY BV (NL) 2000-08-29 US disclosed
US-6054404-A COORDINATION CATALYST MONTELL TECHNOLOGY COMPANY BV (NL) 2000-04-25 US disclosed
US-5786495-A HIGH MOLECULAR WEIGHT ATACTIC POLYPROPYLENE POLYMERIZATION CATALYST MONTELL TECHNOLOGY COMPANY BV (NL) 1998-07-28 US disclosed
EP-0729968-A1 Bridged bis-fluorenyl metallocenes, process for the preparation thereof and use thereof in catalysts for the polymerization of olefins Montell Technology Company bv (NL) 1996-09-04 EP disclosed
EP-0729984-A1 Atactic copolymers of propylene with ethylene Montell Technology Company bv (NL) 1996-09-04 EP disclosed