Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 2/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | PAX8 | Q06710 | 2/20 | 0.46 |
| ▸ | JAK2 | O60674 | 1/20 | 0.46 |
| ▸ | LTA4H | P09960 | 4/20 | 0.46 |
| ▸ | NR5A1 | Q13285 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | GPX4 | P36969 | 1/20 | 0.39 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.39 |
| ▸ | HSD17B3 | P37058 | 5/20 | 0.37 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | ESR1 | P03372 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7199967 | 1.00 | NPC1 (0.46) | NPC1RAB9APAX8JAK2LTA4H | |
| SCHEMBL8627094 | 0.92 | NPC1 (0.52) | NPC1RAB9APAX8JAK2ALDH1A1 | |
| SCHEMBL8624028 | 0.92 | NPC1 (0.52) | NPC1RAB9APAX8JAK2ALDH1A1 | |
| SCHEMBL8624754 | 0.92 | NPC1 (0.52) | NPC1RAB9APAX8JAK2ALDH1A1 | |
| SCHEMBL7200619 | 0.89 | NPC1 (0.49) | NPC1RAB9APAX8JAK2ALDH1A1 | |
| SCHEMBL7198023 | 0.87 | LTA4H (0.50) | NPC1RAB9APAX8JAK2LTA4H | |
| SCHEMBL7197445 | 0.87 | LTA4H (0.50) | NPC1RAB9APAX8JAK2LTA4H | |
| SCHEMBL8623660 | 0.85 | NPC1 (0.46) | NPC1RAB9APAX8JAK2ALDH1A1 | |
| SCHEMBL7197804 | 0.85 | LTA4H (0.48) | NPC1RAB9APAX8JAK2LTA4H | |
| SCHEMBL7197913 | 0.85 | LTA4H (0.48) | NPC1RAB9APAX8JAK2LTA4H |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6596669-B1 | Comprising a support and two reversible heat-sensitive recording layers having different colors formed on the same side of the support, comprising colorless electron-donative dye precursor and an electron-accepting compound | MITSUBISHI PAPER MILLS LIMITED (JP) | 2003-07-22 | — | — | US | disclosed |