Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 3/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | GAA | P10253 | 2/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.49 |
| ▸ | LTA4H | P09960 | 2/20 | 0.49 |
| ▸ | GLA | P06280 | 1/20 | 0.48 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.48 |
| ▸ | EPHX1 | P07099 | 4/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | PSMB11 | A5LHX3 | 2/20 | 0.46 |
| ▸ | PSMA7 | O14818 | 2/20 | 0.46 |
| ▸ | PSMB1 | P20618 | 2/20 | 0.46 |
| ▸ | PSMA1 | P25786 | 2/20 | 0.46 |
| ▸ | PSMA2 | P25787 | 2/20 | 0.46 |
| ▸ | PSMA3 | P25788 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7197799 | 1.00 | HTT (0.51) | HTTSMN1; SMN2LMNAALDH1A1GAA | |
| SCHEMBL8623606 | 0.92 | EPHX1 (0.55) | HTTSMN1; SMN2LMNAALDH1A1GAA | |
| SCHEMBL8624191 | 0.92 | EPHX1 (0.55) | HTTSMN1; SMN2LMNAALDH1A1GAA | |
| SCHEMBL8627419 | 0.92 | EPHX1 (0.55) | HTTSMN1; SMN2LMNAALDH1A1GAA | |
| SCHEMBL7198019 | 0.88 | EPHX1 (0.63) | HTTALDH1A1MAPTKMT2ALTA4H | |
| SCHEMBL7197441 | 0.88 | EPHX1 (0.63) | HTTALDH1A1MAPTKMT2ALTA4H | |
| SCHEMBL7197119 | 0.88 | EPHX1 (0.51) | HTTSMN1; SMN2LMNAALDH1A1GAA | |
| SCHEMBL7197888 | 0.86 | PSMB11 (0.54) | HTTALDH1A1GAAMAPTKMT2A | |
| SCHEMBL7199964 | 0.86 | PSMB11 (0.54) | HTTALDH1A1GAAMAPTKMT2A | |
| SCHEMBL7201045 | 0.85 | LTA4H (0.70) | HTTSMN1; SMN2LTA4H |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6596669-B1 | Comprising a support and two reversible heat-sensitive recording layers having different colors formed on the same side of the support, comprising colorless electron-donative dye precursor and an electron-accepting compound | MITSUBISHI PAPER MILLS LIMITED (JP) | 2003-07-22 | — | — | US | disclosed |