Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDGFRB | P09619 | 12/20 | 0.54 |
| ▸ | HRH3 | Q9Y5N1 | 4/20 | 0.51 |
| ▸ | AURKA | O14965 | 1/20 | 0.48 |
| ▸ | PRKDC | P78527 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | SCN7A | Q01118 | 1/20 | 0.48 |
| ▸ | HRH1 | P35367 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3366898 | 0.84 | PDGFRB (0.78) | PDGFRB | |
| SCHEMBL5907679 | 0.83 | PDGFRB (0.79) | PDGFRB | |
| SCHEMBL5032742 | 0.83 | PDGFRB (0.75) | PDGFRBAURKA | |
| SCHEMBL3364377 | 0.83 | HRH3 (0.53) | PDGFRBHRH3AURKAPRKDCHRH1 | |
| SCHEMBL5907702 | 0.80 | PDGFRB (0.77) | PDGFRB | |
| SCHEMBL3367321 | 0.80 | PRKDC (0.53) | PDGFRBHRH3AURKAPRKDC | |
| SCHEMBL5907743 | 0.79 | PDGFRB (0.78) | PDGFRB | |
| SCHEMBL5907734 | 0.78 | PDGFRB (0.77) | PDGFRB | |
| SCHEMBL227297 | 0.76 | HRH3 (0.85) | HRH3SCN7AHRH1 | |
| SCHEMBL7197970 | 0.76 | PDGFRB (0.47) | PDGFRBPRKDCMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1309569-A2 | NITROGENOUS HETEROCYCLIC COMPOUNDS | Millennium Pharmaceuticals, Inc. (US) | 2003-05-14 | — | — | EP | disclosed |
| WO-2002016362-A2 | NITROGENOUS HETEROCYCLIC COMPOUNDS | COR THERAPEUTICS, INC. (US) | 2002-02-28 | — | — | WO | disclosed |