Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSK3B | P49841 | 5/20 | 0.48 |
| ▸ | GSK3A | P49840 | 3/20 | 0.48 |
| ▸ | CDK1 | P06493 | 2/20 | 0.48 |
| ▸ | CCNB2 | O95067 | 1/20 | 0.48 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.48 |
| ▸ | CCNB3 | Q8WWL7 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4393953 | 0.83 | GSK3B (0.69) | GSK3BGSK3ACDK1CCNB2CCNB1 | |
| SCHEMBL7024712 | 0.79 | JAK3 (0.38) | — | |
| SCHEMBL5092405 | 0.73 | GSK3B (0.55) | GSK3BGSK3ACDK1CCNB2CCNB1 | |
| SCHEMBL5100038 | 0.72 | GSK3B (0.82) | GSK3BGSK3ACDK1CCNB2CCNB1 | |
| SCHEMBL7696009 | 0.72 | GSK3B (0.50) | GSK3BGSK3ACDK1CCNB2CCNB1 | |
| SCHEMBL4992921 | 0.72 | GSK3B (0.73) | GSK3BGSK3ACDK1CCNB2CCNB1 | |
| SCHEMBL4395954 | 0.71 | GSK3B (0.69) | GSK3BGSK3ACDK1CCNB2CCNB1 | |
| SCHEMBL4393950 | 0.70 | GSK3B (0.50) | GSK3BGSK3ACDK1CCNB2CCNB1 | |
| SCHEMBL5095168 | 0.70 | GSK3B (0.69) | GSK3BGSK3ACDK1CCNB2CCNB1 | |
| SCHEMBL7696006 | 0.70 | GSK3B (0.47) | GSK3BGSK3ACDK1CCNB2CCNB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1317433-A2 | INHIBITORS OF GLYCOGEN SYNTHASE KINASE 3 | CHIRON CORPORATION (US) | 2003-06-11 | — | — | EP | disclosed |
| WO-2002020495-A2 | INHIBITORS OF GLYCOGEN SYNTHASE KINASE 3 | CHIRON CORPORATION (US) | 2002-03-14 | — | — | WO | disclosed |