Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSK3B | P49841 | 3/20 | 0.47 |
| ▸ | CDK1 | P06493 | 2/20 | 0.47 |
| ▸ | GSK3A | P49840 | 2/20 | 0.47 |
| ▸ | CCNB2 | O95067 | 1/20 | 0.47 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.47 |
| ▸ | CCNB3 | Q8WWL7 | 1/20 | 0.47 |
| ▸ | KDM1A | O60341 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7696009 | 0.83 | GSK3B (0.50) | GSK3BCDK1GSK3ACCNB2CCNB1 | |
| SCHEMBL7858547 | 0.83 | GSK3B (0.57) | GSK3BCDK1GSK3ACCNB2CCNB1 | |
| SCHEMBL4393953 | 0.82 | GSK3B (0.69) | GSK3BCDK1GSK3ACCNB2CCNB1 | |
| SCHEMBL4403283 | 0.71 | GSK3B (0.67) | GSK3BCDK1GSK3ACCNB2CCNB1 | |
| SCHEMBL5100038 | 0.71 | GSK3B (0.82) | GSK3BCDK1GSK3ACCNB2CCNB1 | |
| SCHEMBL4992921 | 0.71 | GSK3B (0.73) | GSK3BCDK1GSK3ACCNB2CCNB1 | |
| SCHEMBL5089415 | 0.71 | KDM1A (0.42) | GSK3BCDK1GSK3ACCNB2CCNB1 | |
| SCHEMBL5099784 | 0.70 | GSK3B (0.43) | GSK3BCDK1GSK3ACCNB2CCNB1 | |
| SCHEMBL7198082 | 0.70 | GSK3B (0.48) | GSK3BCDK1GSK3ACCNB2CCNB1 | |
| SCHEMBL4395954 | 0.70 | GSK3B (0.69) | GSK3BCDK1GSK3ACCNB2CCNB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6417185-B1 | HETEROCYCLIC ENZYME INHIBITORS | CHIRON CORPORATION | 2002-07-09 | — | — | US | disclosed |