SCHEMBL7198136

SCHEMBL7198136

CCCCOCCCCCCCCCCC(=O)O

nearest known ligand 0.67

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GPR84 Q9NQS5 7/20 0.67
PPARG P37231 7/20 0.67
PPARD Q03181 7/20 0.67
PPARA Q07869 7/20 0.67
HDAC11 Q96DB2 5/20 0.67
TSHR P16473 4/20 0.67
PTPN1 P18031 3/20 0.67
ALDH1A1 P00352 3/20 0.67
TLR2 O60603 2/20 0.67
TDP1 Q9NUW8 2/20 0.67
FABP4 P15090 2/20 0.67
KMT2A Q03164 2/20 0.67
ALOX15 P16050 2/20 0.67
HSD17B10 Q99714 2/20 0.67
SLC22A6 Q4U2R8 1/20 0.67
SLC22A8 Q8TCC7 1/20 0.67
MEN1 O00255 1/20 0.67
ESR1 P03372 1/20 0.67
PDE4A P27815 1/20 0.67
PDE3A Q14432 1/20 0.67

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21062665 1.00 GPR84 (0.67) GPR84PPARGPPARDPPARAHDAC11
SCHEMBL6426089 1.00 GPR84 (0.67) GPR84PPARGPPARDPPARAHDAC11
SCHEMBL8088473 1.00 GPR84 (0.67) GPR84PPARGPPARDPPARAHDAC11
SCHEMBL3216776 1.00 GPR84 (0.67) GPR84PPARGPPARDPPARAHDAC11
SCHEMBL9007925 0.98 GPR84 (0.64) GPR84PPARGPPARDPPARAHDAC11
SCHEMBL446914 0.98 AKR1B1 (0.65) GPR84PPARGPPARDPPARAHDAC11
SCHEMBL23831109 0.96 GPR84 (0.74) GPR84PPARGPPARDPPARAHDAC11
SCHEMBL4815941 0.96 GPR84 (0.74) GPR84PPARGPPARDPPARAHDAC11
SCHEMBL16319776 0.96 GPR84 (0.74) GPR84PPARGPPARDPPARAHDAC11
SCHEMBL2471966 0.96 GPR84 (0.74) GPR84PPARGPPARDPPARAHDAC11

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0327523-B1 NOVEL FATTY ACID ANALOG ENZYME SUBSTRATES WASHINGTON UNIVERSITY (US) 1992-06-17 EP claimed
EP-0327523-A1 Novel fatty acid analog enzyme substrates WASHINGTON UNIVERSITY (US) 1989-08-09 EP claimed
US-6602861-B1 Acylated phospholipid drugs RESEARCH CORPORATION TECHNOLOGIES, INC. 2003-08-05 US disclosed
US-5959145-A 12-(METHOXY)DODECANOIC ACID. WASHINGTON UNIVERSITY (US) 1999-09-28 US disclosed
US-5871954-A ACYLATION OF PEPTIDE OR PROTEIN BY REACTING WITH COENZYME A ESTER OF AN OXY- OR THIO-SUBSTITUTED FATTY ACID ANALOG IN PRESENCE OF N-MYRISTOYL TRANSFERASE WASHINGTON UNIVERSITY (US) 1999-02-16 US disclosed
EP-0636134-B1 NOVEL ACYLATED PHOSPHOLIPID DRUGS RES CORP TECHNOLOGIES INC (US) 1997-12-17 EP disclosed
EP-0636134-A1 NOVEL ACYLATED PHOSPHOLIPID DRUGS RESEARCH CORPORATION TECHNOLOGIES, INC. (US) 1995-02-01 EP disclosed
WO-1993021191-A1 NOVEL ACYLATED PHOSPHOLIPID DRUGS RESEARCH CORPORATION TECHNOLOGIES, INC. (US) 1993-10-28 WO disclosed
EP-0415902-B1 OXY- OR THIO-SUBSTITUTED FATTY ACID ANALOGS FOR USE IN THE TREATMENT OF RETROVIRAL INFECTIONS WASHINGTON UNIVERSITY (US) 1993-03-17 EP disclosed
US-5151445-A Method of inhibiting parasitic activity WASHINGTON UNIVERSITY (US) 1992-09-29 US disclosed
EP-0498783-A2 Method of inhibiting parasitic activity WASHINGTON UNIVERSITY (US) 1992-08-12 EP disclosed
EP-0327523-B1 NOVEL FATTY ACID ANALOG ENZYME SUBSTRATES WASHINGTON UNIVERSITY (US) 1992-06-17 EP disclosed
US-5073571-A Oxy or thio substituted fatty acid or ester WASHINGTON UNIVERSITY (US) 1991-12-17 US disclosed
EP-0415902-A1 Oxy- or thio-substituted fatty acid analogs for use in the treatment of retroviral infections WASHINGTON UNIVERSITY (US) 1991-03-06 EP disclosed
EP-0327523-A1 Novel fatty acid analog enzyme substrates WASHINGTON UNIVERSITY (US) 1989-08-09 EP disclosed