SCHEMBL7198596

SCHEMBL7198596

O=S(=O)(O)CCCc1cccs1.[NaH]

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TAAR1 Q96RJ0 1/20 0.50
SMN1; SMN2 Q16637 3/20 0.43
POLB P06746 3/20 0.43
ALDH1A1 P00352 2/20 0.43
TSHR P16473 2/20 0.43
L3MBTL1 Q9Y468 1/20 0.43
NPC1 O15118 2/20 0.42
ADRA2A P08913 2/20 0.42
ADRA2B P18089 2/20 0.42
ADRA2C P18825 2/20 0.42
HPGD P15428 1/20 0.41
RAB9A P51151 1/20 0.41
CYP2C19 P33261 1/20 0.41
USP2 O75604 1/20 0.40
TDP1 Q9NUW8 1/20 0.39
PTGS1 P23219 1/20 0.39
PTGS2 P35354 1/20 0.39
LMNA P02545 1/20 0.39
PKM P14618 1/20 0.39
CASP3 P42574 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2886265 0.98 TAAR1 (0.52) TAAR1SMN1; SMN2POLBALDH1A1TSHR
SCHEMBL2886363 0.93 TAAR1 (0.50) TAAR1SMN1; SMN2POLBALDH1A1TSHR
SCHEMBL2886309 0.91 TAAR1 (0.48) TAAR1SMN1; SMN2POLBALDH1A1TSHR
SCHEMBL2886603 0.91 TAAR1 (0.48) TAAR1SMN1; SMN2POLBALDH1A1TSHR
SCHEMBL2888284 0.91 TAAR1 (0.48) TAAR1SMN1; SMN2POLBALDH1A1TSHR
SCHEMBL2886419 0.91 TAAR1 (0.48) TAAR1SMN1; SMN2POLBALDH1A1TSHR
SCHEMBL2885625 0.91 TAAR1 (0.48) TAAR1SMN1; SMN2POLBALDH1A1TSHR
SCHEMBL2883324 0.91 TAAR1 (0.48) TAAR1SMN1; SMN2POLBALDH1A1TSHR
SCHEMBL7697993 0.89 TAAR1 (0.48) TAAR1SMN1; SMN2POLBALDH1A1NPC1
SCHEMBL2880966 0.87 TAAR1 (0.50) TAAR1SMN1; SMN2POLBALDH1A1NPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6598966-B2 Method of creating color-changing displays BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM 2003-07-29 US claimed
US-6501587-B1 Method of creating color-changing displays BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM 2002-12-31 US claimed
US-20020141033-A1 Method of creating color-changing displays FERRARIS JOHN P (US) 2002-10-03 US claimed
US-6598966-B2 Method of creating color-changing displays BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM 2003-07-29 US disclosed
US-6501587-B1 Method of creating color-changing displays BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM 2002-12-31 US disclosed
US-20020141033-A1 Method of creating color-changing displays FERRARIS JOHN P (US) 2002-10-03 US disclosed