Ethylene

Ethylene

SCHEMBL7198620

C=C.O=C1NC(=O)c2c1ccc(Br)c2Br

nearest known ligand 0.47

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PARP1 P09874 4/20 0.47
PPOX P50336 1/20 0.41
GSK3B P49841 2/20 0.39
MAOA P21397 5/20 0.37
MAOB P27338 5/20 0.37
WEE1 P30291 2/20 0.36
CHEK1 O14757 1/20 0.36
KDM4E B2RXH2 1/20 0.35
ALDH1A1 P00352 1/20 0.35
GAA P10253 1/20 0.35
HPGD P15428 1/20 0.35
HSD17B10 Q99714 1/20 0.35
CASP3 P42574 2/20 0.34
CASP2 P42575 1/20 0.34
CASP7 P55210 1/20 0.34
CASP6 P55212 1/20 0.34
CASP8 Q14790 1/20 0.34
TDP2 O95551 1/20 0.34
NPSR1 Q6W5P4 1/20 0.33
GRM5 P41594 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3681061 0.96 PARP1 (0.50) PARP1PPOXGSK3BMAOAMAOB
SCHEMBL30969378 0.78 PARP1 (0.46) PARP1PPOXGSK3BMAOAMAOB
SCHEMBL114048 0.78 PARP1 (0.46) PARP1PPOXGSK3BMAOAMAOB
SCHEMBL9382392 0.78 PPOX (0.48) PARP1PPOXGSK3BMAOAMAOB
SCHEMBL7687362 0.76 PARP1 (0.41) PARP1PPOXGSK3BMAOAMAOB
SCHEMBL7687363 0.76 PARP1 (0.44) PARP1PPOXGSK3BMAOAMAOB
SCHEMBL29823991 0.76 PARP1 (0.44) PARP1PPOXGSK3BMAOAMAOB
SCHEMBL7686016 0.75 GSK3B (0.45) PARP1PPOXGSK3BMAOAMAOB
SCHEMBL11518277 0.74 PARP1 (0.43) PARP1PPOXGSK3BMAOAMAOB
SCHEMBL29441220 0.74 PARP1 (0.43) PARP1PPOXGSK3BMAOAMAOB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0848033-B1 Flame-retardant resin composition, and insulated wire, shielded wire and insulating tube comprising the composition SUMITOMO ELECTRIC INDUSTRIES (JP) 2003-11-12 EP claimed
US-20010005731-A1 Flame-retardant resin composition, and insulated wire, shielded wire and insulating tube comprising the composition SUMITOMO ELECTRIC INDUSTRIES, LTD. (JP) 2001-06-28 US claimed
EP-0848033-A1 Flame-retardant resin composition, and insulated wire, shielded wire and insulating tube comprising the composition SUMITOMO ELECTRIC INDUSTRIES, LTD. (JP) 1998-06-17 EP claimed
EP-0848033-B1 Flame-retardant resin composition, and insulated wire, shielded wire and insulating tube comprising the composition SUMITOMO ELECTRIC INDUSTRIES (JP) 2003-11-12 EP disclosed
US-6500508-B2 Thermoplastic resin comprising low density ethylene-alpha-olefin copolymer made using a single-site metallocene catalyst, a halogen-containing flame retardant, and zinc oxide SUMITOMO ELECTRIC FINE POLYMER, INC. (JP) 2002-12-31 US disclosed
US-20010005731-A1 Flame-retardant resin composition, and insulated wire, shielded wire and insulating tube comprising the composition SUMITOMO ELECTRIC INDUSTRIES, LTD. (JP) 2001-06-28 US disclosed
US-6204318-B1 Insulated wire comprising a flame-retardant polyolefinic resin composition SUMITOMO ELECTRIC INDUSTRIES, LTD. (JP) 2001-03-20 US disclosed
EP-0848033-A1 Flame-retardant resin composition, and insulated wire, shielded wire and insulating tube comprising the composition SUMITOMO ELECTRIC INDUSTRIES, LTD. (JP) 1998-06-17 EP disclosed