SCHEMBL7198796

SCHEMBL7198796

CC1=CC=C2SC(C)=C(C)C12.CC1=Cc2c(ccc3ccccc23)C1[SiH3]

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7197739 0.88 KDM4E (0.32)
SCHEMBL9249191 0.81 ALDH1A1 (0.41)
SCHEMBL7197741 0.81
SCHEMBL7039024 0.71
SCHEMBL28529430 0.67 ALDH1A1 (0.36)
SCHEMBL7201471 0.67
Hydrochloric Acid SCHEMBL28529022 0.65 ALDH1A1 (0.34)
SCHEMBL3965890 0.65 ALDH1A1 (0.42)
SCHEMBL28529021 0.64 CA12 (0.33)
SCHEMBL8673527 0.63 CYP2A6 (0.42)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6620953-B1 Complexing dimethylbis(2-methyl-4,5-benzoindenyl)silane with transition metal compounds such as 2,4-di-tert-butylphenoxide, zirconium monochloride, to form polymerization catalysts BASSELL POLYOLEFINE GMBH (DE) 2003-09-16 US disclosed