Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRD1 | P41143 | 9/20 | 0.49 |
| ▸ | OPRK1 | P41145 | 5/20 | 0.48 |
| ▸ | OPRM1 | P35372 | 4/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7198825 | 0.88 | OPRD1 (0.53) | OPRD1OPRK1OPRM1KCNH2 | |
| SCHEMBL7198440 | 0.88 | OPRD1 (0.64) | OPRD1OPRK1OPRM1ALDH1A1KCNH2 | |
| SCHEMBL6598891 | 0.84 | OPRD1 (0.58) | OPRD1OPRK1OPRM1ALDH1A1KCNH2 | |
| SCHEMBL6598904 | 0.80 | OPRD1 (0.75) | OPRD1OPRK1OPRM1 | |
| SCHEMBL6601274 | 0.78 | OPRD1 (0.60) | OPRD1OPRK1OPRM1CYP2D6KCNH2 | |
| SCHEMBL6599265 | 0.78 | OPRD1 (0.59) | OPRD1OPRK1OPRM1ALDH1A1CYP2D6 | |
| SCHEMBL6598126 | 0.77 | OPRD1 (0.58) | OPRD1OPRK1OPRM1 | |
| SCHEMBL6600513 | 0.76 | OPRD1 (0.51) | OPRD1OPRK1OPRM1ALDH1A1CYP2D6 | |
| SCHEMBL7227860 | 0.75 | OPRD1 (0.56) | OPRD1OPRK1OPRM1 | |
| SCHEMBL5784349 | 0.74 | OPRD1 (0.73) | OPRD1OPRK1OPRM1KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6586431-B1 | Treating drug abuse and drug dependence; nervous system and gastrointestinal disorders | PFIZER INC | 2003-07-01 | — | — | US | disclosed |