Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MME | P08473 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | PTPN1 | P18031 | 9/20 | 0.33 |
| ▸ | PPM1B | O75688 | 1/20 | 0.33 |
| ▸ | ACE | P12821 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | USP2 | O75604 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.31 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.31 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.31 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.31 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5482178 | 0.95 | MME (0.43) | MMECYP1A2CYP2C19ACEALDH1A1 | |
| SCHEMBL4536010 | 0.89 | MME (0.39) | MMECYP1A2CYP2C19PTPN1USP2 | |
| SCHEMBL8818955 | 0.87 | MME (0.42) | MMECYP1A2CYP2C19PPM1BMAPK1 | |
| SCHEMBL5142303 | 0.85 | MME (0.40) | MMECYP1A2CYP2C19PPM1BMAPK1 | |
| SCHEMBL3622599 | 0.85 | MME (0.40) | MMECYP1A2CYP2C19PPM1BMAPK1 | |
| SCHEMBL2325576 | 0.85 | MME (0.40) | MMECYP1A2CYP2C19PPM1BMAPK1 | |
| SCHEMBL859388 | 0.81 | MME (0.46) | MMECYP1A2CYP2C19PPM1BALDH1A1 | |
| SCHEMBL19646439 | 0.78 | TP53 (0.35) | ACEUSP2ALDH1A1LMNAHSP90AA1 | |
| SCHEMBL454925 | 0.76 | MME (0.42) | MMEACEMAPT | |
| SCHEMBL9291274 | 0.76 | MME (0.44) | MMECYP1A2CYP2C19ACEMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003104424-A2 | NOVEL MOLECULAR CONJUGATES FOR SIGNAL AMPLIFICATION | THE GOVERNMENT OF THE UNITED STATES, AS REPRESENTED BY THE SECRETARY OF THE DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) | 2003-12-18 | — | — | WO | disclosed |