Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MME | P08473 | 1/20 | 0.43 |
| ▸ | GPR84 | Q9NQS5 | 3/20 | 0.36 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.36 |
| ▸ | ACE | P12821 | 3/20 | 0.35 |
| ▸ | MAPT | P10636 | 3/20 | 0.35 |
| ▸ | LCK | P06239 | 1/20 | 0.35 |
| ▸ | PPARD | Q03181 | 1/20 | 0.35 |
| ▸ | ZDHHC20 | Q5W0Z9 | 1/20 | 0.35 |
| ▸ | ZDHHC2 | Q9UIJ5 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | HPGD | P15428 | 2/20 | 0.34 |
| ▸ | HTT | P42858 | 2/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.33 |
| ▸ | PTGER4 | P35408 | 5/20 | 0.33 |
| ▸ | PTGER3 | P43115 | 4/20 | 0.33 |
| ▸ | PTGER2 | P43116 | 4/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7199030 | 0.95 | MME (0.45) | MMEACEMAPTALDH1A1LMNA | |
| SCHEMBL4536010 | 0.93 | MME (0.39) | MMEFFAR1MAPTPPARDALDH1A1 | |
| SCHEMBL5142303 | 0.88 | MME (0.40) | MMEALDH1A1HPGDHSD17B10PTGER4 | |
| SCHEMBL2325576 | 0.88 | MME (0.40) | MMEALDH1A1HPGDHSD17B10PTGER4 | |
| SCHEMBL3622599 | 0.88 | MME (0.40) | MMEALDH1A1HPGDHSD17B10PTGER4 | |
| SCHEMBL8818955 | 0.85 | MME (0.42) | MMEALDH1A1HPGDHSD17B10KDM4E | |
| SCHEMBL19646439 | 0.84 | TP53 (0.35) | ACEMAPTALDH1A1LMNAHPGD | |
| SCHEMBL9291274 | 0.82 | MME (0.44) | MMEGPR84FFAR1ACEMAPT | |
| SCHEMBL859388 | 0.79 | MME (0.46) | MMEALDH1A1CYP1A2CYP2C19 | |
| SCHEMBL3475153 | 0.77 | ALDH1A1 (0.31) | MAPTALDH1A1LMNAHPGDHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8792985-B2 | Gastrointestinal methods and apparatus for use in treating disorders and controlling blood sugar | METACURE LIMITED (BM) | 2014-07-29 | — | — | US | disclosed |
| US-20070027493-A1 | Gastrointestinal methods and apparatus for use in treating disorders and controlling blood sugar | TYLERTON INTERNATIONAL, INC. (VG) | 2007-02-01 | — | — | US | disclosed |
| EP-1646423-A2 | GASTROINTESTINAL METHODS AND APPARATUS FOR USE IN TREATING DISORDERS AND CONTROLLING BLOOD SUGAR | Metacure NV (AN) | 2006-04-19 | — | — | EP | disclosed |
| WO-2005007232-A2 | GASTROINTESTINAL METHODS AND APPARATUS FOR USE IN TREATING DISORDERS AND CONTROLLING BLOOD SUGAR | METACURE N.V. (AN) | 2005-01-27 | — | — | WO | disclosed |