Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR4A2 | P43354 | 2/20 | 0.47 |
| ▸ | MRGPRX4 | Q96LA9 | 7/20 | 0.45 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.44 |
| ▸ | NR4A3 | Q92570 | 1/20 | 0.44 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | KDM4C | Q9H3R0 | 4/20 | 0.42 |
| ▸ | FABP3 | P05413 | 1/20 | 0.41 |
| ▸ | FABP4 | P15090 | 1/20 | 0.41 |
| ▸ | FABP5 | Q01469 | 1/20 | 0.41 |
| ▸ | PTGER1 | P34995 | 3/20 | 0.40 |
| ▸ | KDM5A | P29375 | 3/20 | 0.40 |
| ▸ | KDM5B | Q9UGL1 | 3/20 | 0.40 |
| ▸ | KDM4A | O75164 | 1/20 | 0.38 |
| ▸ | KDM2B | Q8NHM5 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4642486 | 0.92 | HDAC8 (0.45) | NR4A2MRGPRX4NR4A1NR4A3HDAC8 | |
| SCHEMBL5597418 | 0.84 | MRGPRX4 (0.36) | NR4A2MRGPRX4LMNAFABP3FABP4 | |
| SCHEMBL5597310 | 0.80 | FPR2 (0.44) | MRGPRX4PTGER1KDM5AKDM5B | |
| SCHEMBL4642508 | 0.78 | MRGPRX4 (0.39) | NR4A2MRGPRX4LMNAHTTPTGER1 | |
| SCHEMBL2777367 | 0.77 | NR4A2 (0.45) | NR4A2MRGPRX4NR4A1NR4A3HDAC8 | |
| SCHEMBL7199087 | 0.74 | NR4A2 (0.51) | NR4A2MRGPRX4NR4A1NR4A3HDAC8 | |
| SCHEMBL4642228 | 0.73 | FPR2 (0.44) | MRGPRX4PTGER1KDM5AKDM5B | |
| SCHEMBL4640765 | 0.71 | FPR2 (0.40) | — | |
| SCHEMBL4642685 | 0.70 | FPR2 (0.47) | LMNAHTT | |
| SCHEMBL2353051 | 0.69 | HDAC8 (0.44) | HDAC8LMNAHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003082299-A1 | IMPROVED HORMONE REPLACEMENT THERAPY | JENCAP RESEARCH LTD. (CA) | 2003-10-09 | — | — | WO | disclosed |