Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 19/20 | 0.54 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | CA4 | P22748 | 1/20 | 0.39 |
| ▸ | CA6 | P23280 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13377702 | 0.74 | PARP1 (0.77) | PARP1CA1CA2CA4CA6 | |
| SCHEMBL7203370 | 0.72 | PARP1 (0.67) | PARP1 | |
| SCHEMBL13377548 | 0.71 | PARP1 (0.77) | PARP1CA1CA2CA4CA6 | |
| SCHEMBL8274291 | 0.71 | PARP1 (0.77) | PARP1CA1CA2CA4CA6 | |
| SCHEMBL29496073 | 0.71 | PARP1 (0.77) | PARP1CA1CA2CA4CA6 | |
| SCHEMBL2763098 | 0.71 | PARP1 (0.77) | PARP1CA1CA2CA4CA6 | |
| SCHEMBL14079328 | 0.71 | PARP1 (0.62) | PARP1CA1CA2CA4CA6 | |
| SCHEMBL7197461 | 0.71 | PARP1 (0.54) | PARP1 | |
| SCHEMBL13377549 | 0.69 | PARP1 (0.56) | PARP1 | |
| SCHEMBL2763788 | 0.69 | PARP1 (0.65) | PARP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030096833-A1 | Substituted ideno[1,2-c]isoquinoline derivatives and methods of use thereof | INOTEK PHARMACEUTICALS CORPORATION | 2003-05-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030096833-A1 | Substituted ideno[1,2-c]isoquinoline derivatives and methods of use thereof | UGT1A1, XPO1, IPO7 | PARP1 833/4885CA1 4597/4885CA2 3994/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.