Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 20/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7203370 | 0.76 | PARP1 (0.67) | PARP1 | |
| SCHEMBL13377699 | 0.74 | PARP1 (0.59) | PARP1 | |
| SCHEMBL13377702 | 0.74 | PARP1 (0.77) | PARP1 | |
| SCHEMBL2763788 | 0.73 | PARP1 (0.65) | PARP1 | |
| SCHEMBL8274291 | 0.71 | PARP1 (0.77) | PARP1 | |
| SCHEMBL2763098 | 0.71 | PARP1 (0.77) | PARP1 | |
| SCHEMBL13377548 | 0.71 | PARP1 (0.77) | PARP1 | |
| SCHEMBL29496073 | 0.71 | PARP1 (0.77) | PARP1 | |
| SCHEMBL4965180 | 0.71 | PARP1 (0.60) | PARP1 | |
| SCHEMBL7199106 | 0.71 | PARP1 (0.54) | PARP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6603031-B1 | Active metabolites of vitamin D2 and vitamin D3 and their synthetic derivatives have a proliferation- inhibiting and differentiation-stimulating action on tumor cells and normal cells, | SCHERING AKTIENGESELLSCHAFT (DE) | 2003-08-05 | — | — | US | disclosed |