Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 2/20 | 0.45 |
| ▸ | ALOX5AP | P20292 | 2/20 | 0.39 |
| ▸ | PDE3B | Q13370 | 4/20 | 0.37 |
| ▸ | PDE3A | Q14432 | 4/20 | 0.37 |
| ▸ | PDE2A | O00408 | 3/20 | 0.37 |
| ▸ | THRB | P10828 | 2/20 | 0.37 |
| ▸ | P2RY12 | Q9H244 | 1/20 | 0.36 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.36 |
| ▸ | PLA2G2A | P14555 | 3/20 | 0.36 |
| ▸ | THRA | P10827 | 1/20 | 0.35 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.35 |
| ▸ | PLA2G4B | P0C869 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6491422 | 0.91 | PPARG (0.51) | PPARGALOX5APPDE3BPDE3APDE2A | |
| SCHEMBL6492145 | 0.91 | PPARG (0.51) | PPARGALOX5APPDE3BPDE3APDE2A | |
| SCHEMBL6500098 | 0.90 | PPARG (0.50) | PPARGALOX5APPDE3BPDE3APDE2A | |
| SCHEMBL7197584 | 0.89 | PPARG (0.42) | PPARGALOX5APTHRBPLA2G2ATHRA | |
| SCHEMBL6498744 | 0.89 | PPARG (0.51) | PPARGALOX5APPDE3BPDE3APDE2A | |
| SCHEMBL6487612 | 0.85 | PPARG (0.51) | PPARGALOX5APMCL1PLA2G4B | |
| SCHEMBL7196842 | 0.85 | PPARG (0.47) | PPARGALOX5APPDE2ATHRBTHRA | |
| SCHEMBL7199168 | 0.85 | PPARG (0.47) | PPARGALOX5APPDE2ATHRBTHRA | |
| SCHEMBL6491237 | 0.84 | FFAR1 (0.49) | PPARGALOX5APPDE3BPDE3APDE2A | |
| SCHEMBL6501485 | 0.84 | PPARG (0.45) | PPARGALOX5APPDE3BPDE3APDE2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004108686-A2 | BENZIMIDAZOLE COMPOUNDS HAVING HYPOGLYCEMIC ACTIVITY | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2004-12-16 | — | — | WO | disclosed |