Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.49 |
| ▸ | LMNA | P02545 | 5/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.48 |
| ▸ | CA1 | P00915 | 2/20 | 0.45 |
| ▸ | CA2 | P00918 | 2/20 | 0.45 |
| ▸ | CA7 | P43166 | 2/20 | 0.45 |
| ▸ | CA9 | Q16790 | 2/20 | 0.45 |
| ▸ | HTT | P42858 | 2/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.41 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL916100 | 0.88 | CA1 (0.49) | ALDH1A1LMNAKMT2ACA1CA2 | |
| SCHEMBL917030 | 0.86 | CA12 (0.47) | ALDH1A1LMNAKMT2ACA1CA2 | |
| SCHEMBL915399 | 0.85 | CA1 (0.48) | ALDH1A1LMNAKMT2ACA1CA2 | |
| SCHEMBL915681 | 0.85 | ALDH1A1 (0.55) | ALDH1A1LMNAKMT2ACA1CA2 | |
| SCHEMBL915664 | 0.85 | KMT2A (0.50) | ALDH1A1LMNAKMT2ACA1CA2 | |
| SCHEMBL2066512 | 0.84 | KMT2A (0.58) | ALDH1A1LMNAKMT2AHTTCYP1A2 | |
| SCHEMBL916837 | 0.83 | KMT2A (0.47) | ALDH1A1LMNAKMT2AHTTCYP1A2 | |
| SCHEMBL915009 | 0.83 | ALDH1A1 (0.51) | ALDH1A1LMNAKMT2AHTTCYP1A2 | |
| SCHEMBL915975 | 0.83 | MAPT (0.53) | ALDH1A1LMNAKMT2AHTTMAPT | |
| SCHEMBL916886 | 0.83 | KMT2A (0.58) | ALDH1A1LMNAKMT2AHTTCYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6599943-B1 | Preventive treatment, related to the radical generating nature of the xanthine dehydrogenase/xanthine oxidase | WAPHARM AB (SE) | 2003-07-29 | — | — | US | disclosed |
| EP-1007025-A1 | USE OF HYDROXYGUANIDINES | Wa Pharm AB (SE) | 2000-06-14 | — | — | EP | disclosed |
| WO-1998023267-A1 | USE OF HYDROXYGUANIDINES | WAPHARM AB (SE) | 1998-06-04 | — | — | WO | disclosed |