Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIN2D | O15399 | 3/20 | 0.62 |
| ▸ | GRIN3B | O60391 | 3/20 | 0.62 |
| ▸ | GRIN1 | Q05586 | 3/20 | 0.62 |
| ▸ | GRIN2A | Q12879 | 3/20 | 0.62 |
| ▸ | GRIN2B | Q13224 | 3/20 | 0.62 |
| ▸ | GRIN2C | Q14957 | 3/20 | 0.62 |
| ▸ | GRIN3A | Q8TCU5 | 3/20 | 0.62 |
| ▸ | HRH4 | Q9H3N8 | 7/20 | 0.59 |
| ▸ | AKR1C3 | P42330 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7171812 | 0.82 | GRIN2D (0.68) | GRIN2DGRIN3BGRIN1GRIN2AGRIN2B | |
| SCHEMBL7169459 | 0.79 | GRIN2D (0.74) | GRIN2DGRIN3BGRIN1GRIN2AGRIN2B | |
| SCHEMBL7158407 | 0.77 | GRIN2D (1.00) | GRIN2DGRIN3BGRIN1GRIN2AGRIN2B | |
| SCHEMBL7160016 | 0.76 | GRIN2D (0.72) | GRIN2DGRIN3BGRIN1GRIN2AGRIN2B | |
| SCHEMBL29979972 | 0.75 | CHRM2 (0.49) | GRIN2B | |
| SCHEMBL18429013 | 0.75 | CHRM2 (0.49) | GRIN2B | |
| SCHEMBL27283741 | 0.73 | KMT2A (0.51) | GRIN2B | |
| SCHEMBL27258963 | 0.72 | SRD5A1 (0.48) | GRIN2B | |
| SCHEMBL27393302 | 0.70 | BLM (0.51) | GRIN2B | |
| SCHEMBL16599052 | 0.69 | HRH4 (0.71) | HRH4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1328514-A1 | AMIDE DERIVATIVES AS NMDA RECEPTOR ANTAGONISTS | RICHTER GEDEON VEGYESZETI GYAR R.T. (HU) | 2003-07-23 | — | — | EP | disclosed |
| WO-2002034718-A1 | AMIDE DERIVATIVES AS NMDA RECEPTOR ANTAGONISTS | RICHTER GEDEON VEGYESZETI GYAR RT. (HU) | 2002-05-02 | — | — | WO | disclosed |