Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 | P08172 | 1/20 | 0.49 |
| ▸ | HTR1A | P08908 | 1/20 | 0.49 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.49 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.49 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.49 |
| ▸ | DRD1 | P21728 | 1/20 | 0.49 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.49 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.49 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.49 |
| ▸ | DRD3 | P35462 | 1/20 | 0.49 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.49 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.49 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.46 |
| ▸ | SRD5A1 | P18405 | 1/20 | 0.44 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.44 |
| ▸ | ACHE | P22303 | 1/20 | 0.43 |
| ▸ | MGLL | Q99685 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18429013 | 1.00 | CHRM2 (0.49) | CHRM2HTR1AADRA2ACYP2D6CHRM1 | |
| SCHEMBL27283741 | 0.90 | KMT2A (0.51) | CHRM2HTR1AADRA2ACYP2D6CHRM1 | |
| SCHEMBL27258963 | 0.88 | SRD5A1 (0.48) | CHRM2HTR1AADRA2ACYP2D6CHRM1 | |
| SCHEMBL28086941 | 0.87 | DPP4 (0.42) | KCNH2MGLLMEN1KMT2A | |
| SCHEMBL27393302 | 0.86 | BLM (0.51) | CHRM2HTR1AADRA2ACYP2D6CHRM1 | |
| SCHEMBL9926016 | 0.84 | SLC6A2 (0.64) | CHRM2HTR1AADRA2ACYP2D6CHRM1 | |
| SCHEMBL18428984 | 0.84 | GPR119 (0.56) | MAPK1KDM4EALDH1A1MEN1KMT2A | |
| SCHEMBL18469978 | 0.81 | CHRM1 (0.73) | CHRM2HTR1AADRA2ACYP2D6CHRM1 | |
| SCHEMBL9356595 | 0.80 | SLC6A3 (0.58) | CHRM2HTR1AADRA2ACYP2D6CHRM1 | |
| SCHEMBL27177320 | 0.79 | HRH3 (0.43) | CHRM2CYP2D6CHRM1HRH3ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4284365-A1 | CDK2 INHIBITORS AND METHODS OF USING THE SAME | Cedilla Therapeutics, Inc. (US) | 2023-12-06 | — | — | EP | disclosed |
| WO-2022165513-A1 | CDK2 INHIBITORS AND METHODS OF USING THE SAME | CEDILLA THERAPEUTICS, INC. (US) | 2022-08-04 | — | — | WO | disclosed |