⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27554888 | 0.79 | — | — | |
| SCHEMBL5509975 | 0.72 | — | — | |
| SCHEMBL9169132 | 0.72 | — | — | |
| Hydrochloric Acid SCHEMBL28329543 | 0.69 | — | — | |
| Water SCHEMBL28099894 | 0.69 | — | — | |
| SCHEMBL4590882 | 0.67 | — | — | |
| SCHEMBL27510308 | 0.67 | — | — | |
| Alcohol SCHEMBL4436479 | 0.65 | ALDH1A1 (0.38) | — | |
| SCHEMBL130624 | 0.65 | — | — | |
| SCHEMBL5697006 | 0.63 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-54106078-A | — | — | None | — | — | JP | disclosed |
| US-6593466-B1 | Monomer of given formula; modified to increase binding affinity to target DNA or RNA and resist nuclease degradation; useful as therapeutics or diagnostics; gene expression inhibition | ISIS PHARMACEUTICALS, INC. | 2003-07-15 | — | — | US | disclosed |
| EP-1206574-A4 | GUANIDINIUM FUNCTIONALIZED OLIGOMERS AND METHODS | ISIS PHARMACEUTICALS INC (US) | 2002-10-16 | — | — | EP | disclosed |
| EP-1206574-A2 | GUANIDINIUM FUNCTIONALIZED OLIGOMERS AND METHODS | ISIS PHARMACEUTICALS, INC. (US) | 2002-05-22 | — | — | EP | disclosed |
| WO-2001002423-A9 | 2'-GUANIDINYL-SUBSTITUTED OLIGONUCLEOTIDES AND GENE EXPRESSION MODULATION THEREWITH | ISIS PHARMACEUTICALS INC (US) | 2002-05-02 | — | — | WO | disclosed |
| WO-2001002423-A2 | 2'-GUANIDINYL-SUBSTITUTED OLIGONUCLEOTIDES AND GENE EXPRESSION MODULATION THEREWITH | ISIS PHARMACEUTICALS, INC. (US) | 2001-01-11 | — | — | WO | disclosed |
| JP-S54106078-A | CATHODE FOR ELECTROLIZING AQUEOUS ALKALI METAL HALOGENIDE SOLUTION AND MANUFACTURE THEREOF | SHOWA DENKO KK | 1979-08-20 | — | — | JP | disclosed |