⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1328556 | 0.83 | TDP1 (0.31) | — | |
| SCHEMBL16327711 | 0.77 | ALDH1A1 (0.41) | — | |
| SCHEMBL28038699 | 0.72 | — | — | |
| SCHEMBL28235551 | 0.72 | — | — | |
| SCHEMBL14390529 | 0.72 | — | — | |
| SCHEMBL12105733 | 0.72 | — | — | |
| SCHEMBL12348388 | 0.72 | — | — | |
| SCHEMBL9241020 | 0.72 | — | — | |
| SCHEMBL19774819 | 0.69 | — | — | |
| SCHEMBL6559461 | 0.67 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 29 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112979704-A | Voriconazole phosphocholine inner salt key intermediate and preparation method thereof | 重庆西米瑞医药技术有限公司 | 2021-06-18 | — | — | CN | claimed |
| CN-119504896-A | N-acetylgalactosamine modified pentaerythritol derivatives for oligonucleotide capping, methods of preparing the same, delivery compounds and nucleotide drugs | 上海兆维科技发展有限公司 | 2025-02-25 | — | — | CN | disclosed |
| WO-2023192828-A2 | COMPOSITIONS AND METHODS FOR THE TREATMENT OF ANGIOPOIETIN LIKE 7 (ANGPTL7) RELATED DISEASES | EMPIRICO INC. (US) | 2023-10-05 | — | — | WO | disclosed |
| WO-2023277168-A1 | POLYNUCLEOTIDE AND MEDICINAL COMPOSITION | 協和キリン株式会社 | 2023-01-05 | — | — | WO | disclosed |
| EP-3573718-B1 | CYCLIC DINUCLEOTIDES AS STING AGONISTS | JANSSEN BIOTECH INC (US) | 2022-06-01 | — | — | EP | disclosed |
| EP-3919619-A1 | MULTI-TARGETED SINGLE ENTITY CONJUGATES | Alnylam Pharmaceuticals, Inc. (US) | 2021-12-08 | — | — | EP | disclosed |
| CN-113004328-A | Voriconazole phosphocholine inner salt intermediate, preparation method and method for preparing voriconazole phosphocholine inner salt | 重庆西米瑞医药技术有限公司 | 2021-06-22 | — | — | CN | disclosed |
| CN-112979704-A | Voriconazole phosphocholine inner salt key intermediate and preparation method thereof | 重庆西米瑞医药技术有限公司 | 2021-06-18 | — | — | CN | disclosed |
| EP-3569711-B1 | LIGAND-MODIFIED DOUBLE-STRANDED NUCLEIC ACIDS | DICERNA PHARMACEUTICALS INC (US) | 2021-02-03 | — | — | EP | disclosed |
| EP-3744350-A1 | NUCLEIC ACID LINKED TO A TRIVALENT GLYCOCONJUGATE | Silence Therapeutics GmbH (DE) | 2020-12-02 | — | — | EP | disclosed |
| US-20150051167-A1 | SUBSTITUTED NUCLEOSIDES, NUCLEOTIDES AND ANALOGS THEREOF | Janssen Biopharma, Inc. | 2015-02-19 | — | — | US | disclosed |
| US-20150011497-A1 | SUBSTITUTED NUCLEOSIDES, NUCLEOTIDES AND ANALOGS THEREOF | Janssen Pharmaceuticals, Inc. | 2015-01-08 | — | — | US | disclosed |
| WO-2014209979-A1 | SUBSTITUTED NUCLEOSIDES, NUCLEOTIDES AND ANALOGS THEREOF | ALIOS BIOPHARMA, INC. (US) | 2014-12-31 | — | — | WO | disclosed |
| US-8822671-B2 | 2'-O-modified RNA | THE UNIVERSITY OF TOKYO (JP) | 2014-09-02 | — | — | US | disclosed |
| US-20130253178-A1 | 2'-O-MODIFIED RNA | THE UNIVERSITY OF TOKYO (JP) | 2013-09-26 | — | — | US | disclosed |
| US-20130165400-A1 | SUBSTITUTED NUCLEOSIDES, NUCLEOTIDES AND ANALOGS THEREOF | ALIOS BIOPHARMA, INC. (US) | 2013-06-27 | — | — | US | disclosed |
| US-6605708-B1 | Stability | HYBRIDON, INC. | 2003-08-12 | — | — | US | disclosed |
| EP-0700449-A1 | INVERSE LINKAGE OLIGONUCLEOTIDES FOR CHEMICAL AND ENZYMATIC PROCESSES | BECKMAN INSTRUMENTS, INC. (US) | 1996-03-13 | — | — | EP | disclosed |
| US-5462854-A | Amenable to enzymatic elongation from either, or most preferably both termini under appropriate conditions and in presence of polymerase enzyme | BECKMAN INSTRUMENTS, INC. (US) | 1995-10-31 | — | — | US | disclosed |
| WO-1994024312-A2 | INVERSE LINKAGE OLIGONUCLEOTIDES FOR CHEMICAL AND ENZYMATIC PROCESSES | BECKMAN INSTRUMENTS, INC. (US) | 1994-10-27 | — | — | WO | disclosed |