SCHEMBL7199668

SCHEMBL7199668

Cc1ccnc(C(=O)O)c1C

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 10/20 0.47
ASPH Q12797 5/20 0.47
KDM8 Q8N371 5/20 0.47
ALDH1A1 P00352 5/20 0.45
MAPT P10636 4/20 0.45
L3MBTL1 Q9Y468 2/20 0.45
CYP3A4 P08684 1/20 0.45
ALOX15 P16050 1/20 0.45
TSHR P16473 1/20 0.45
BLM P54132 1/20 0.45
AGER Q15109 1/20 0.45
NPSR1 Q6W5P4 1/20 0.45
NOS3 P29474 1/20 0.45
NOS2 P35228 1/20 0.45
MYC P01106 1/20 0.44
CYP1A2 P05177 1/20 0.40
KMT2A Q03164 1/20 0.40
KMO O15229 1/20 0.39
LMNA P02545 1/20 0.39
NAPRT Q6XQN6 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6169072 0.83 NOS3 (0.45) KDM4EASPHKDM8ALDH1A1MAPT
SCHEMBL14284234 0.81 KDM4E (0.46) KDM4EASPHKDM8ALDH1A1MAPT
SCHEMBL30631992 0.81 NOS3 (0.48) KDM4ENOS3NOS2KMT2ALMNA
SCHEMBL28313767 0.81 KDM4E (0.46) KDM4EASPHKDM8ALDH1A1MAPT
SCHEMBL19857487 0.81 KDM4E (0.60) KDM4EASPHKDM8ALDH1A1MAPT
SCHEMBL1437221 0.81 NOS3 (0.48) KDM4ENOS3NOS2KMT2ALMNA
SCHEMBL1541111 0.81 KDM4E (0.46) KDM4EASPHKDM8ALDH1A1MAPT
SCHEMBL30049082 0.81 KDM4E (0.50) KDM4EASPHKDM8ALDH1A1MAPT
SCHEMBL9684174 0.81 KDM4E (0.50) KDM4EASPHKDM8ALDH1A1MAPT
Hydrochloric Acid SCHEMBL16741076 0.79 NOS3 (0.47) KDM4ENOS3NOS2KMT2ALMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 33 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116943617-A Dimethyl pyridinamine modified nano magnetic bead and preparation method and application thereof 广东千祺生物科技有限公司 2023-10-27 CN claimed
CN-110794647-A Photosensitive resin composition and preparation method thereof 臻鼎科技股份有限公司 2020-02-14 CN claimed
EP-0744395-B1 PROCESS FOR PRODUCING DIMETHYLAMINE MITSUBISHI RAYON CO (JP) 2001-10-31 EP claimed
EP-3927427-B1 LANTHIONINE C-LIKE PROTEIN 2 LIGANDS, CELLS PREPARED THEREWITH, AND THERAPIES USING SAME NIMMUNE BIOPHARMA INC (US) 2024-02-07 EP disclosed
CN-116943617-A Dimethyl pyridinamine modified nano magnetic bead and preparation method and application thereof 广东千祺生物科技有限公司 2023-10-27 CN disclosed
CN-113748109-B Lanthionine C-like protein 2 ligands, cells prepared with said ligands and therapies using said ligands 朗多生物制药股份有限公司 2023-07-21 CN disclosed
CN-109689848-B Fragrance composition 奇华顿股份有限公司 2022-12-23 CN disclosed
US-11377437-B2 Lanthionine C-like protein 2 ligands, cells prepared therewith, and therapies using same LANDOS BIOPHARMA, INC. (US) 2022-07-05 US disclosed
EP-3927427-A1 LANTHIONINE C-LIKE PROTEIN 2 LIGANDS, CELLS PREPARED THEREWITH, AND THERAPIES USING SAME LANDOS BIOPHARMA, INC. (US) 2021-12-29 EP disclosed
CN-113748109-A Lanthionine C-like protein 2 ligands, cells prepared with said ligands and therapies using said ligands 朗多生物制药股份有限公司 2021-12-03 CN disclosed
US-20210355101-A1 LANTHIONINE C-LIKE PROTEIN 2 LIGANDS, CELLS PREPARED THEREWITH, AND THERAPIES USING SAME LANDOS BIOPHARMA, INC. (US) 2021-11-18 US disclosed
US-5952532-A CONTACTING AROMATIC FEEDSTOCK WITH OXIDANT COMPRISING MOLECULAR OXYGEN IN PRESENCE OF A CATALYST COMPRISING A SUPPORT, TRANSITIONAL METALS AND A MULTIDENTATE CHELATING BINUCLEATING LIGAND AS PROMOTER SUNOCO, INC. (US) 1999-09-14 US disclosed
US-5861536-A USING A CATALYST COMPRISING A SUPPORT, TRANSITION METAL; AND A MONO- OR BINUCLEATING LIGAND COMPRISING AT LEAST ONE NITRO OR NITROSO GROUP SUN COMPANY, INC. (R&M) (US) 1999-01-19 US disclosed
US-5741802-A FOR TREATMENT OF MEMORY LOSS UNIVERSITY OF FLORIDA (US) 1998-04-21 US disclosed
EP-0659078-A4 ANABASEINE DERIVATIVES USEFUL IN THE TREATMENT OF DEGENERATIVE DISEASES OF THE NERVOUS SYSTEM. UNIV FLORIDA (US) 1996-04-24 EP disclosed
EP-0659078-A1 ANABASEINE DERIVATIVES USEFUL IN THE TREATMENT OF DEGENERATIVE DISEASES OF THE NERVOUS SYSTEM UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. (US) 1995-06-28 EP disclosed
WO-1994005288-A1 ANABASEINE DERIVATIVES USEFUL IN THE TREATMENT OF DEGENERATIVE DISEASES OF THE NERVOUS SYSTEM UNIVERSITY OF FLORIDA (US) 1994-03-17 WO disclosed
US-4104274-A 1-Substituted-2-(2-pyridinyl)ethanone N-oxides WARNER-LAMBERT COMPANY (US) 1978-08-01 US disclosed
US-4076720-A 1-Substituted-2-(2-pyridinyl)ethanone N-oxides WARNER-LAMBERT COMPANY (US) 1978-02-28 US disclosed
US-4056619-A 1-Substituted-2-(2-pyridinyl)ethanone N-oxides WARNER-LAMBERT COMPANY (US) 1977-11-01 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11377437-B2 Lanthionine C-like protein 2 ligands, cells prepared therewith, and therapies using same LCP2, LANCL2, SSB KDM4E 3905/4885ASPH 2875/4885KDM8 2239/4885
US-20210355101-A1 LANTHIONINE C-LIKE PROTEIN 2 LIGANDS, CELLS PREPARED THEREWITH, AND THERAPIES USING SAME LCP2, LANCL2, SSB KDM4E 3905/4885ASPH 2875/4885KDM8 2239/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.