Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.39 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | PAX8 | Q06710 | 2/20 | 0.39 |
| ▸ | KLF5 | Q13887 | 2/20 | 0.39 |
| ▸ | NR2F2 | P24468 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 7/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 6/20 | 0.38 |
| ▸ | PKM | P14618 | 4/20 | 0.38 |
| ▸ | CDK5 | Q00535 | 3/20 | 0.38 |
| ▸ | CDK5R1 | Q15078 | 3/20 | 0.38 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | MITF | O75030 | 1/20 | 0.38 |
| ▸ | PPARG | P37231 | 2/20 | 0.37 |
| ▸ | PPARA | Q07869 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20935416 | 0.91 | ALDH1A1 (0.46) | KMT2AALDH1A1MAPK1PAX8KLF5 | |
| SCHEMBL29201237 | 0.90 | ALDH1A1 (0.45) | KMT2AALDH1A1MAPK1TDP1PAX8 | |
| SCHEMBL245812 | 0.90 | ALDH1A1 (0.45) | KMT2AALDH1A1MAPK1TDP1PAX8 | |
| SCHEMBL14429957 | 0.90 | ALDH1A1 (0.45) | KMT2AALDH1A1MAPK1TDP1PAX8 | |
| SCHEMBL28486023 | 0.89 | ALDH1A1 (0.42) | KMT2AALDH1A1MAPK1PAX8KLF5 | |
| SCHEMBL27996751 | 0.86 | KMT2A (0.49) | KMT2AALDH1A1MAPK1PAX8RAB9A | |
| SCHEMBL28478924 | 0.83 | NR2F2 (0.45) | KMT2AALDH1A1MAPK1PAX8KLF5 | |
| SCHEMBL28831707 | 0.83 | HAO1 (0.43) | KMT2AALDH1A1MAPK1KLF5RAB9A | |
| SCHEMBL14429952 | 0.82 | ALDH1A1 (0.45) | KMT2AALDH1A1MAPK1KLF5RAB9A | |
| SCHEMBL12328370 | 0.80 | ALDH1A1 (0.43) | KMT2AALDH1A1MAPK1TDP1PAX8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6596445-B1 | Initiators for photopolymerization of radically polymerizable compounds | CIBA SPECIALTY CHEMICALS CORPORATION | 2003-07-22 | — | — | US | disclosed |