Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.35 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.35 |
| ▸ | CASP3 | P42574 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.35 |
| ▸ | RELA | Q04206 | 1/20 | 0.35 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.35 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.35 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28623994 | 0.80 | ALDH1A1 (0.42) | ALDH1A1NPC1PLA2G1BNFKB1CASP3 | |
| SCHEMBL714735 | 0.78 | ALDH1A1 (0.47) | ALDH1A1NPC1PLA2G1BNFKB1CASP3 | |
| SCHEMBL21631842 | 0.76 | ALDH1A1 (0.45) | ALDH1A1NPC1PLA2G1BNFKB1CASP3 | |
| SCHEMBL27862672 | 0.76 | ALDH1A1 (0.45) | ALDH1A1NPC1PLA2G1BNFKB1CASP3 | |
| SCHEMBL21244337 | 0.76 | ALDH1A1 (0.45) | ALDH1A1NPC1PLA2G1BNFKB1CASP3 | |
| SCHEMBL27727744 | 0.76 | ALDH1A1 (0.45) | ALDH1A1NPC1PLA2G1BNFKB1CASP3 | |
| SCHEMBL9412832 | 0.74 | NPC1 (0.38) | ALDH1A1NPC1PLA2G1BNFKB1CASP3 | |
| SCHEMBL12473636 | 0.73 | — | — | |
| SCHEMBL7947236 | 0.73 | — | — | |
| SCHEMBL28868288 | 0.72 | ALDH1A1 (0.42) | ALDH1A1NPC1PLA2G1BNFKB1CASP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1297027-A1 | SILOXY SUBSTITUTED COCATALYST ACTIVATORS FOR OLEFIN POLYMERIZATION | Exxonmobil Chemical Patents Inc. (US) | 2003-04-02 | — | — | EP | disclosed |
| WO-2002000738-A1 | SILOXY SUBSTITUTED COCATALYST ACTIVATORS FOR OLEFIN POLYMERIZATION | EXXONMOBIL CHEMICAL PATENTS INC. (US) | 2002-01-03 | — | — | WO | disclosed |