Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | NR2F2 | P24468 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10753763 | 0.94 | MAPT (0.44) | MAPTKDM4ESMN1; SMN2KMT2AMEN1 | |
| SCHEMBL10981678 | 0.90 | MAPT (0.41) | MAPTKDM4ESMN1; SMN2KMT2AMEN1 | |
| SCHEMBL11117488 | 0.86 | NPC1 (0.47) | MAPTKDM4ESMN1; SMN2KMT2AMEN1 | |
| SCHEMBL10755866 | 0.86 | KMT2A (0.45) | MAPTKDM4ESMN1; SMN2KMT2AMEN1 | |
| SCHEMBL10751811 | 0.86 | MAPT (0.45) | MAPTKDM4ESMN1; SMN2KMT2AMEN1 | |
| SCHEMBL10751205 | 0.86 | SMN1; SMN2 (0.45) | MAPTKDM4ESMN1; SMN2KMT2AMEN1 | |
| Chlorobenzene SCHEMBL10753772 | 0.84 | MAPT (0.47) | MAPTKDM4ESMN1; SMN2KMT2AMEN1 | |
| SCHEMBL10749743 | 0.84 | MAPT (0.47) | MAPTKDM4ESMN1; SMN2KMT2AMEN1 | |
| SCHEMBL10752620 | 0.84 | KMT2A (0.48) | MAPTKDM4ESMN1; SMN2KMT2AMEN1 | |
| SCHEMBL10752114 | 0.83 | MAPT (0.46) | MAPTKDM4ESMN1; SMN2KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4261729-A | Herbicidal compositions and pyrazole derivatives | SANKYO COMPANY LIMITED (JP) | 1981-04-14 | — | — | US | claimed |
| US-20030191025-A1 | Herbicidal compositions with substituted phenylsulfonylureas for controlling weeds in rice | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2003-10-09 | — | — | US | disclosed |
| US-4687858-A | HERBICIDES | SANKYO COMPANY LIMITED (JP) | 1987-08-18 | — | — | US | disclosed |
| US-4508910-A | Herbicidal 4-benzoyl-5-hydroxy-pyrazales | SANKYO COMPANY LTD. (JP) | 1985-04-02 | — | — | US | disclosed |
| US-4414392-A | Herbicidal compositions and pyrazole derivatives | SANKYO COMPANY, LTD. (JP) | 1983-11-08 | — | — | US | disclosed |
| US-4301293-A | Herbicidal compositions and pyrazole derivatives | SANKYO COMPANY LTD. (JP) | 1981-11-17 | — | — | US | disclosed |
| US-4146726-A | HERBICIDES | SANKYO COMPANY LIMITED (JP) | 1979-03-27 | — | — | US | disclosed |
| US-4063925-A | Herbicidal compositions | SANKYO COMPANY LIMITED (JA) | 1977-12-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030191025-A1 | Herbicidal compositions with substituted phenylsulfonylureas for controlling weeds in rice | DDT, CYCS, CBR3 | MAPT 4704/4885KDM4E 235/4885SMN1; SMN2 2949/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.