Known targets — ChEMBL curated mechanism
ACHECHRM1CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNG
The experimentally established mechanism targets of Iodide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM1 known ✓ | P11229 | 1/20 | 0.35 |
| ▸ | CHRM3 known ✓ | P20309 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 1.00 |
| ▸ | LMNA | P02545 | 3/20 | 0.46 |
| ▸ | APOBEC3A | P31941 | 3/20 | 0.46 |
| ▸ | APOBEC3G | Q9HC16 | 3/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | CDC25A | P30304 | 1/20 | 0.44 |
| ▸ | CHRNB2 | P17787 | 4/20 | 0.42 |
| ▸ | CHRNA4 | P43681 | 4/20 | 0.42 |
| ▸ | CHRNB4 | P30926 | 3/20 | 0.42 |
| ▸ | CHRNA3 | P32297 | 3/20 | 0.42 |
| ▸ | CHRNA7 | P36544 | 3/20 | 0.42 |
| ▸ | CHRNA10 | Q9GZZ6 | 3/20 | 0.42 |
| ▸ | CHRNA9 | Q9UGM1 | 3/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 3/20 | 0.38 |
| ▸ | CTDSP1 | Q9GZU7 | 2/20 | 0.38 |
| ▸ | BBOX1 | O75936 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Iodide SCHEMBL14877089 | 1.00 | KDM4E (1.00) | KDM4ELMNAAPOBEC3AAPOBEC3GKMT2A | |
| SCHEMBL372822 | 0.98 | KDM4E (0.95) | KDM4ELMNAAPOBEC3AAPOBEC3GKMT2A | |
| Iodide SCHEMBL14876646 | 0.98 | KDM4E (0.95) | KDM4ELMNAAPOBEC3AAPOBEC3GKMT2A | |
| SCHEMBL718386 | 0.98 | KDM4E (0.95) | KDM4ELMNAAPOBEC3AAPOBEC3GKMT2A | |
| Bromide SCHEMBL2354539 | 0.95 | KDM4E (0.91) | KDM4ELMNAAPOBEC3AAPOBEC3GKMT2A | |
| Water SCHEMBL15375367 | 0.95 | KDM4E (0.91) | KDM4ELMNAAPOBEC3AAPOBEC3GKMT2A | |
| SCHEMBL372602 | 0.95 | KDM4E (0.91) | KDM4ELMNAAPOBEC3AAPOBEC3GKMT2A | |
| Hydrochloric Acid SCHEMBL17022299 | 0.93 | KDM4E (0.86) | KDM4ELMNAAPOBEC3AAPOBEC3GKMT2A | |
| Bromide SCHEMBL717429 | 0.93 | KDM4E (0.86) | KDM4ELMNAAPOBEC3AAPOBEC3GKMT2A | |
| SCHEMBL23484985 | 0.90 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8345407-B2 | Low viscosity ionic liquids | INVISTA NORTH AMERICA S.A R.L. (US) | 2013-01-01 | — | — | US | disclosed |
| EP-2534134-A1 | LOW VISCOSITY IONIC LIQUIDS | Invista Technologies S.à.r.l. (CH) | 2012-12-19 | — | — | EP | disclosed |
| US-20120050945-A1 | LOW VISCOSITY IONIC LIQUIDS | INVISTA NORTH AMERICA S.A R.L. (US) | 2012-03-01 | — | — | US | disclosed |
| WO-2011100232-A1 | LOW VISCOSITY IONIC LIQUIDS | INVISTA TECHNOLOGIES S.A R.L. (CH) | 2011-08-18 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120050945-A1 | LOW VISCOSITY IONIC LIQUIDS | H1-3, H1-0, H1-2 | CHRM1 30/4885CHRM3 40/4885KDM4E 1489/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.