Bromide

Bromide

SCHEMBL717429

COCC[N+]1(C)CCCC1.[Br-]

nearest known ligand 0.86

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

ACHECHKACHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNB1CHRNDCHRNECHRNGHRH2OPRM1

The experimentally established mechanism targets of Bromide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ACHE known ✓ P22303 2/20 0.35
KDM4E B2RXH2 2/20 0.86
CDC25A P30304 1/20 0.41
TP53 P04637 1/20 0.40
LMNA P02545 4/20 0.39
APOBEC3A P31941 2/20 0.39
APOBEC3G Q9HC16 2/20 0.39
KMT2A Q03164 2/20 0.39
BBOX1 O75936 2/20 0.39
CHRNA7 P36544 4/20 0.38
CHRNB2 P17787 3/20 0.38
CHRNB4 P30926 3/20 0.38
CHRNA3 P32297 3/20 0.38
CHRNA4 P43681 3/20 0.38
CHRNA10 Q9GZZ6 3/20 0.38
CHRNA9 Q9UGM1 3/20 0.38
HTT P42858 2/20 0.34
CTDSP1 Q9GZU7 2/20 0.33
CYP3A4 P08684 1/20 0.32
TSHR P16473 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Bromide SCHEMBL2354539 0.98 KDM4E (0.91) KDM4ECDC25ATP53LMNAAPOBEC3A
SCHEMBL372602 0.97 KDM4E (0.91) KDM4ECDC25ATP53LMNAAPOBEC3A
SCHEMBL372822 0.95 KDM4E (0.95) KDM4ECDC25ATP53LMNAAPOBEC3A
Iodide SCHEMBL14876646 0.95 KDM4E (0.95) KDM4ECDC25ATP53LMNAAPOBEC3A
Hydrochloric Acid SCHEMBL17022299 0.95 KDM4E (0.86) KDM4ECDC25ATP53LMNAAPOBEC3A
SCHEMBL718386 0.95 KDM4E (0.95) KDM4ECDC25ATP53LMNAAPOBEC3A
Iodide SCHEMBL14877089 0.93 KDM4E (1.00) KDM4ECDC25ATP53LMNAAPOBEC3A
Water SCHEMBL15375367 0.93 KDM4E (0.91) KDM4ECDC25ATP53LMNAAPOBEC3A
Iodide SCHEMBL720052 0.93 KDM4E (1.00) KDM4ECDC25ATP53LMNAAPOBEC3A
SCHEMBL23484985 0.92

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3103156-B1 GELATED IONIC LIQUID FILM-COATED SURFACES AND USES THEREOF GELION TECH PTY LTD (AU) 2019-06-12 EP disclosed
US-20190097273-A1 GELATED IONIC LIQUID FILM-COATED SURFACES AND USES THEREOF GELION TECH PTY LTD (AU) 2019-03-28 US disclosed
US-10122049-B2 Gelated ionic liquid film-coated surfaces and uses thereof GELION TECHNOLOGIES PTY LTD (AU) 2018-11-06 US disclosed
EP-3103156-A1 GELATED IONIC LIQUID FILM-COATED SURFACES AND USES THEREOF Gelion Technologies PTY LTD (AU) 2016-12-14 EP disclosed
US-20160351969-A1 GELATED IONIC LIQUID FILM-COATED SURFACES AND USES THEREOF GELION TECHNOLOGIES PTY LTD (AU) 2016-12-01 US disclosed
EP-2172463-B1 Quaternary ammonium salt, electrolytic solution and electrochemical device OTSUKA CHEMICAL CO LTD (JP) 2015-06-17 EP disclosed
US-8747690-B2 Quaternary ammonium salt and composition, and electrochemical device OTSUKA CHEMICAL CO., LTD. (JP) 2014-06-10 US disclosed
US-8366956-B2 Quaternary ammonium salt and composition, and electrochemical device OTSUKA CHEMICAL CO., LTD. (JP) 2013-02-05 US disclosed
US-20130004860-A1 QUATERNARY AMMONIUM SALT AND COMPOSITION, AND ELECTROCHEMICAL DEVICE STELLA CHEMIFA CORPORATION (JP) 2013-01-03 US disclosed
US-8345407-B2 Low viscosity ionic liquids INVISTA NORTH AMERICA S.A R.L. (US) 2013-01-01 US disclosed
EP-2172463-A1 Quaternary ammonium salt, electrolytic solution and electrochemical device Otsuka Chemical Co., Ltd. (JP) 2010-04-07 EP disclosed
EP-1840124-B1 QUATERNARY AMMONIUM SALT, ELECTROLYTE, ELECTROLYTE SOLUTION AND ELECTROCHEMICAL DEVICE OTSUKA CHEMICAL CO LTD (JP) 2010-03-17 EP disclosed
US-20100038578-A1 Quaternary ammonium salt, electrolyte, electrolyte solution and electrochemical device ALLY BANK, AS AGENT 2010-02-18 US disclosed
US-20080050657-A1 N-methoxymethyl-N-methylpyrrolidinium trifluoromethanesulfonate; high solubility in organic solvents, high electroconductivity, voltage resistance; environmentally friendly; use in lithium battery; double layer capacitors STELLA CHEMIFA CORPORATION (JP) 2008-02-28 US disclosed
EP-1840124-A1 QUATERNARY AMMONIUM SALT, ELECTROLYTE, ELECTROLYTE SOLUTION AND ELECTROCHEMICAL DEVICE Otsuka Chemical Co., Ltd. (JP) 2007-10-03 EP disclosed
EP-1837333-A1 QUATERNARY AMMONIUM SALT, ELECTROLYTE, ELECTROLYTE SOLUTION AND ELECTROCHEMICAL DEVICE Otsuka Chemical Co., Ltd. (JP) 2007-09-26 EP disclosed
US-20070099079-A1 Ionic liquid, method for producing same, double layer capacitor comprising same, and lithium battery NATIONAL INSTITUTE OF ADVANCED INDUSTRIAL SCIENCE AND TECHNOLOGY (JP) 2007-05-03 US disclosed
US-20070042271-A1 Quaternary ammonium salt, electrolyte, and electrochemical device OTSUKA CHEMICAL CO., LTD. (JP) 2007-02-22 US disclosed
EP-1698631-A1 IONIC LIQUID, METHOD FOR PRODUCING SAME, DOUBLE LAYER CAPACITOR COMPRISING SAME, AND LITHIUM BATTERY National Institute of Advanced Industrial Science and Technology (JP) 2006-09-06 EP disclosed
EP-1642894-A1 QUATERNARY AMMONIUM SALT, ELECTROLYTE, AND ELECTROCHEMICAL DEVICE OTSUKA CHEMICAL COMPANY, LIMITED (JP) 2006-04-05 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070099079-A1 Ionic liquid, method for producing same, double layer capacitor comprising same, and lithium battery CLCN2, CACNA1F, CACNB3 ACHE 1320/4885KDM4E 2047/4885CDC25A 2091/4885
US-20080050657-A1 N-methoxymethyl-N-methylpyrrolidinium trifluoromethanesulfonate; high solubility in organic solvents, high electroconductivity, voltage resistance; environmentally friendly; use in lithium battery; double layer capacitors CACNA1F, KCNN2, KCNN3 ACHE 3272/4885KDM4E 942/4885CDC25A 2509/4885
US-20070042271-A1 Quaternary ammonium salt, electrolyte, and electrochemical device DNMT3A, NHERF1, SLC9A1 ACHE 2602/4885KDM4E 448/4885CDC25A 3561/4885
US-20100038578-A1 Quaternary ammonium salt, electrolyte, electrolyte solution and electrochemical device SCN1B, SCN1A, SCN11A ACHE 2539/4885KDM4E 1433/4885CDC25A 3649/4885
US-20130004860-A1 QUATERNARY AMMONIUM SALT AND COMPOSITION, AND ELECTROCHEMICAL DEVICE DNMT3A, AFF4, AFF2 ACHE 2379/4885KDM4E 291/4885CDC25A 3674/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.