Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | GFER | P55789 | 1/20 | 0.41 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.41 |
| ▸ | DRD1 | P21728 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.37 |
| ▸ | MEN1 | O00255 | 4/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.37 |
| ▸ | ATM | Q13315 | 2/20 | 0.37 |
| ▸ | PKM | P14618 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | CCR6 | P51684 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10921779 | 0.79 | DRD1 (0.39) | DRD1MEN1KMT2AATMLMNA | |
| SCHEMBL29184903 | 0.78 | ESR1 (0.46) | TSHR | |
| SCHEMBL6168264 | 0.76 | CA1 (0.46) | ALDH1A1MAPK1TSHRL3MBTL1MAPT | |
| SCHEMBL7205487 | 0.76 | PDE2A (0.42) | ALOX15ALDH1A1MEN1KMT2ALMNA | |
| SCHEMBL11491256 | 0.76 | SCN9A (0.38) | ALDH1A1MEN1KMT2ALMNAL3MBTL1 | |
| SCHEMBL13859437 | 0.74 | ALOX15 (0.44) | ALOX15GFERADAM17DRD1ALDH1A1 | |
| SCHEMBL18290854 | 0.74 | KMT2A (0.45) | ALOX15GFERADAM17DRD1ALDH1A1 | |
| SCHEMBL19416608 | 0.74 | ALOX15 (0.44) | ALOX15GFERADAM17DRD1ALDH1A1 | |
| SCHEMBL11065049 | 0.73 | DRD1 (0.56) | ALOX15GFERADAM17DRD1ALDH1A1 | |
| SCHEMBL6965069 | 0.73 | SRD5A2 (0.54) | TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6605730-B2 | 3-(2-Thienyl)-5-phenyl-1H-pyrazole compounds of given formula | NIHON BAYER AGROCHEM K.K. (JP) | 2003-08-12 | — | — | US | disclosed |
| US-20030028034-A1 | Nematicidal pyrazoles | WADA KATSUAKI (JP) | 2003-02-06 | — | — | US | disclosed |
| US-6310049-B1 | 3-(2-THIENYL),5-(SUBSTITUTED PHENYL)-1H-PYRAZOLES AND 3-(SUBSTITUTED PHENYL),5-(2-THIENYL)-1H-PYRAZOLES OF GIVEN FORMULA; ANTHELMINTICS | NIHON BAYER AGROCHEM K.K. (JP) | 2001-10-30 | — | — | US | disclosed |
| EP-1104418-A2 | NEMATICIDAL PYRAZOLES | NIHON BAYER AGROCHEM K.K. (JP) | 2001-06-06 | — | — | EP | disclosed |
| WO-2000009500-A2 | NEMATICIDAL PYRAZOLES | NIHON BAYER AGROCHEM K.K. (JP) | 2000-02-24 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030028034-A1 | Nematicidal pyrazoles | CBR3, CBR1, CCR4 | ALOX15 1095/4885GFER 369/4885ADAM17 4851/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.