Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.48 |
| ▸ | PLK1 | P53350 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | HPGD | P15428 | 2/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.45 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.44 |
| ▸ | SPHK1 | Q9NYA1 | 5/20 | 0.44 |
| ▸ | SPHK2 | Q9NRA0 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | RARB | P10826 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | THRA | P10827 | 1/20 | 0.42 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
| ▸ | CA12 | O43570 | 1/20 | 0.42 |
| ▸ | CA1 | P00915 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
| ▸ | CA9 | Q16790 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27700861 | 0.83 | HRH3 (0.49) | HRH3ALDH1A1KCNA3SMN1; SMN2 | |
| SCHEMBL8048203 | 0.83 | MEN1 (0.57) | PLK1ALDH1A1HPGDHSD17B10MEN1 | |
| SCHEMBL5389754 | 0.83 | ALDH1A1 (0.50) | PLK1ALDH1A1HPGDHSD17B10MEN1 | |
| SCHEMBL23582666 | 0.82 | HRH3 (0.48) | HRH3ALDH1A1SMN1; SMN2CA1CA2 | |
| SCHEMBL27551549 | 0.81 | ALDH1A1 (0.49) | PLK1ALDH1A1HPGDHSD17B10MEN1 | |
| SCHEMBL25380968 | 0.81 | HRH3 (0.46) | HRH3ALDH1A1KCNA3SMN1; SMN2 | |
| SCHEMBL23582817 | 0.81 | HRH3 (0.47) | HRH3ALDH1A1SMN1; SMN2 | |
| SCHEMBL5988607 | 0.80 | ALDH1A1 (0.48) | HRH3ALDH1A1KCNA3SMN1; SMN2CA1 | |
| SCHEMBL480053 | 0.80 | HRH3 (0.45) | HRH3ALDH1A1KCNA3SMN1; SMN2 | |
| SCHEMBL27730677 | 0.78 | HRH3 (0.56) | HRH3ALDH1A1POLBSMN1; SMN2THRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6596716-B2 | 2-propane-sulphonamide derivatives | ELI LILLY AND COMPANY | 2003-07-22 | — | — | US | disclosed |