SCHEMBL7200973

SCHEMBL7200973

C=Cc1ccc(O)c(C(C)(C)C)c1C(C)(C)C

nearest known ligand 0.35

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 6/20 0.34
ALOX15 P16050 3/20 0.34
HSD17B10 Q99714 2/20 0.34
TDP1 Q9NUW8 2/20 0.34
HPGD P15428 2/20 0.34
MAPT P10636 4/20 0.34
SMN1; SMN2 Q16637 2/20 0.34
NR1I2 O75469 1/20 0.33
LMNA P02545 1/20 0.33
CYP2C9 P11712 1/20 0.33
MIF P14174 1/20 0.33
TYR P14679 1/20 0.33
HTT P42858 1/20 0.33
NFE2L2 Q16236 1/20 0.33
SLC22A8 Q8TCC7 3/20 0.33
ESR1 P03372 2/20 0.33
ESR2 Q92731 2/20 0.33
SLC22A6 Q4U2R8 2/20 0.33
TRPA1 O75762 1/20 0.32
MEN1 O00255 2/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6651196 0.82 MAPT (0.32) ALDH1A1ALOX15HSD17B10TDP1HPGD
SCHEMBL11437773 0.82 ALDH1A1 (0.39) ALDH1A1ALOX15HSD17B10TDP1HPGD
SCHEMBL1552308 0.79 ERN1 (0.40) ALDH1A1ALOX15HSD17B10TDP1HPGD
SCHEMBL30027143 0.79 ALDH1A1 (0.48) ALDH1A1ALOX15HSD17B10TDP1HPGD
SCHEMBL70068 0.79 ALDH1A1 (0.48) ALDH1A1ALOX15HSD17B10TDP1HPGD
SCHEMBL4068356 0.77
SCHEMBL7115432 0.75 ESR1 (0.33) ESR1ESR2
SCHEMBL3661990 0.75
SCHEMBL28409231 0.73 ALDH1A1 (0.41) ALDH1A1TDP1TSHR
SCHEMBL5694506 0.72 ALDH1A1 (0.42) ALDH1A1ALOX15HSD17B10TDP1HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0808334-B1 PROPYLENE PENTENE-1 COPOLYMERS, METHOD OF PREPARATION THEREOF AND COMPOSITION CONTAINING THEM SASOL TECH PTY LTD (ZA) 2003-11-26 EP disclosed
US-6391951-B1 MIXTURE CONTAINING PHENOLIC STABILIZER SASOL TECHNOLOGY (PROPRIETARY) LIMITED (ZA) 2002-05-21 US disclosed
EP-0808334-A1 PROPYLENE PENTENE-1 COPOLYMERS, METHOD OF PREPARATION THEREOF AND COMPOSITION CONTAINING THEM Sasol Technology (Proprietary) Limited (ZA) 1997-11-26 EP disclosed
WO-1996024623-A1 PROPYLENE PENTENE-1 COPOLYMERS, METHOD OF PREPARATION THEREOF AND COMPOSITION CONTAINING THEM SASTECH (PROPRIETARY) LIMITED (ZA) 1996-08-15 WO disclosed
EP-0204964-B1 2-PYRROLIDONE DERIVATIVES, PROCESS FOR PREPARING THEM, PHARMACEUTICAL COMPOSITION AND USE Eisai Co., Ltd. (JP) 1991-08-28 EP disclosed