Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.50 |
| ▸ | HPGD | P15428 | 2/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | S1PR2 | O95136 | 2/20 | 0.47 |
| ▸ | S1PR1 | P21453 | 2/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | RARB | P10826 | 1/20 | 0.46 |
| ▸ | PLK1 | P53350 | 1/20 | 0.46 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.46 |
| ▸ | THRA | P10827 | 1/20 | 0.45 |
| ▸ | THRB | P10828 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL903613 | 0.94 | S1PR1 (0.55) | ALDH1A1HSD17B10MEN1KMT2AS1PR2 | |
| SCHEMBL29681728 | 0.91 | TDP1 (0.51) | ALDH1A1TDP1MEN1KMT2APOLB | |
| SCHEMBL9670491 | 0.88 | TDP1 (0.57) | ALDH1A1HPGDHSD17B10TDP1MEN1 | |
| SCHEMBL11276809 | 0.86 | MEN1 (0.59) | ALDH1A1HPGDTDP1MEN1KMT2A | |
| SCHEMBL10566989 | 0.85 | TDP1 (0.51) | ALDH1A1HPGDHSD17B10TDP1MEN1 | |
| SCHEMBL10757869 | 0.85 | CYP4F2 (0.60) | ALDH1A1TDP1MEN1KMT2APOLB | |
| SCHEMBL10755378 | 0.85 | CYP4F2 (0.47) | ALDH1A1TDP1MEN1KMT2APOLB | |
| SCHEMBL8841177 | 0.84 | MEN1 (0.48) | ALDH1A1HPGDTDP1MEN1KMT2A | |
| SCHEMBL7614444 | 0.84 | MEN1 (0.62) | TDP1MEN1KMT2AS1PR1S1PR3 | |
| SCHEMBL11275239 | 0.83 | TDP1 (0.47) | ALDH1A1HPGDTDP1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003027064-A1 | SIMPLIFIED RESINIFERATOXIN ANALOGUES AS VANILLOID RECEPTOR AGONIST SHOWING EXCELLENT ANALGESIC ACTIVITY AND THE PHARMACEUTICAL CO MPOSITIONS CONTAINING THE SAME | DIGITAL BIOTECH CO. LTD,. (KR) | 2003-04-03 | — | — | WO | disclosed |