Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 4/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.59 |
| ▸ | TDP1 | Q9NUW8 | 6/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.46 |
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.45 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.45 |
| ▸ | MMP8 | P22894 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.42 |
| ▸ | STAT3 | P40763 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29681728 | 0.94 | TDP1 (0.51) | MEN1KMT2ATDP1MAPK1L3MBTL1 | |
| SCHEMBL11205643 | 0.90 | MEN1 (0.65) | MEN1KMT2ATDP1MAPK1L3MBTL1 | |
| SCHEMBL10755378 | 0.88 | CYP4F2 (0.47) | MEN1KMT2ATDP1MAPK1L3MBTL1 | |
| SCHEMBL10757869 | 0.88 | CYP4F2 (0.60) | MEN1KMT2ATDP1MAPK1L3MBTL1 | |
| SCHEMBL11275239 | 0.86 | TDP1 (0.47) | MEN1KMT2ATDP1MAPK1L3MBTL1 | |
| SCHEMBL7201044 | 0.86 | ALDH1A1 (0.50) | MEN1KMT2ATDP1MAPK1L3MBTL1 | |
| SCHEMBL11271408 | 0.86 | EPHX2 (0.46) | MEN1KMT2ATDP1MAPK1L3MBTL1 | |
| SCHEMBL935980 | 0.86 | TDP1 (0.59) | MEN1KMT2ATDP1MAPK1L3MBTL1 | |
| SCHEMBL10758873 | 0.85 | TDP1 (0.44) | MEN1KMT2ATDP1MAPK1L3MBTL1 | |
| SCHEMBL10755297 | 0.85 | TDP1 (0.48) | MEN1KMT2ATDP1MAPK1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015107548-A1 | IMPROVED FINGOLIMOD PROCESS | EMCURE PHARMACEUTICALS LIMITED (IN) | 2015-07-23 | — | — | WO | disclosed |
| EP-0064244-A1 | Spermicidal 1-bis(arylalkyl)alkylimidazoles | SYNTEX (U.S.A.) INC. (US) | 1982-11-10 | — | — | EP | disclosed |