SCHEMBL7201051

SCHEMBL7201051

Cc1ccc(S(=O)(=O)NCCCNS(=O)(=O)c2ccc(C)cc2)cc1

nearest known ligand 0.86

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 15/20 0.86
CA12 O43570 1/20 0.74
CA2 P00918 1/20 0.74
CA9 Q16790 1/20 0.74
ALOX15 P16050 1/20 0.72
MEN1 O00255 2/20 0.70
KMT2A Q03164 2/20 0.70
MBTD1 Q05BQ5 1/20 0.66
L3MBTL1 Q9Y468 1/20 0.66
NPSR1 Q6W5P4 1/20 0.65
GAA P10253 2/20 0.63
MAPT P10636 1/20 0.63
HTT P42858 2/20 0.62
LMNA P02545 2/20 0.62
HPGD P15428 1/20 0.62
PKM P14618 1/20 0.59

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7094852 0.96 ALDH1A1 (0.79) ALDH1A1CA12CA2CA9ALOX15
SCHEMBL7095731 0.94 ALDH1A1 (0.77) ALDH1A1CA12CA2CA9ALOX15
SCHEMBL7097551 0.94 ALDH1A1 (0.77) ALDH1A1CA12CA2CA9ALOX15
SCHEMBL7095949 0.94 ALDH1A1 (0.77) ALDH1A1CA12CA2CA9ALOX15
SCHEMBL7093365 0.94 ALDH1A1 (0.77) ALDH1A1CA12CA2CA9ALOX15
SCHEMBL7095193 0.94 ALDH1A1 (0.77) ALDH1A1CA12CA2CA9ALOX15
SCHEMBL7092896 0.94 ALDH1A1 (0.77) ALDH1A1CA12CA2CA9ALOX15
SCHEMBL11808676 0.93 ALDH1A1 (0.75) ALDH1A1CA12CA2CA9ALOX15
SCHEMBL812683 0.93 ALDH1A1 (0.75) ALDH1A1CA12CA2CA9ALOX15
SCHEMBL5567042 0.91 ALDH1A1 (0.75) ALDH1A1CA12CA2CA9ALOX15

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 161 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10301258-B2 Benzende sulfonamide derivatives as HIV integrase inhibitors HOWARD UNIVERSITY (US) 2019-05-28 US claimed
US-4929530-A OXIDATIVE LEUCO DYES, PHOTO-OXIDIZERS, REDUCING AGENTS, ORGANIC SULFONAMIDES AND PHENOLIC COMPONENTS; EXPOSING TO LIGHT FUJI PHOTO FILM CO., LTD. (JP) 1990-05-29 US claimed
CN-116970187-B Preparation method of carboxyl cellulose composite hydrogel containing nitrogen crown ether 常熟威怡科技有限公司 2024-01-23 CN disclosed
CN-116970187-A Preparation method of carboxyl cellulose composite hydrogel containing nitrogen crown ether 常熟威怡科技有限公司 2023-10-31 CN disclosed
US-20230288610-A1 WAVELENGTH SELECTIVE ABSORPTION FILTER AND DISPLAY DEVICE FUJIFILM CORPORATION (JP) 2023-09-14 US disclosed
US-20230288610-A1 WAVELENGTH SELECTIVE ABSORPTION FILTER AND DISPLAY DEVICE FUJIFILM CORPORATION (JP) 2023-09-14 US disclosed
EP-4225447-A1 MODULATORS OF CYSTIC FIBROSIS TRANSMEMBRANE CONDUCTANCE REGULATOR Vertex Pharmaceuticals Incorporated (US) 2023-08-16 EP disclosed
WO-2022076625-A1 MODULATORS OF CYSTIC FIBROSIS TRANSMEMBRANE CONDUCTANCE REGULATOR VERTEX PHARMACEUTICALS INCORPORATED (US) 2022-04-14 WO disclosed
US-10301258-B2 Benzende sulfonamide derivatives as HIV integrase inhibitors HOWARD UNIVERSITY (US) 2019-05-28 US disclosed
US-10301258-B2 Benzende sulfonamide derivatives as HIV integrase inhibitors HOWARD UNIVERSITY (US) 2019-05-28 US disclosed
US-9726932-B2 Optical film, optical compensation film, polarizing plate and liquid crystal display FUJIFILM CORPORATION (JP) 2017-08-08 US disclosed
US-6319956-B1 N1, N4-BIS(CYCLOPROPYLMETHYLAMINO)TRIALKYLENETETRAMINES THAT MAY BE TOLUENESULFONATED. RIKEN (JP) 2001-11-20 US disclosed
US-5399455-A Electrophotographic toner composition and image fixing process FUJI XEROX CO., LTD. (JP) 1995-03-21 US disclosed
US-4929530-A OXIDATIVE LEUCO DYES, PHOTO-OXIDIZERS, REDUCING AGENTS, ORGANIC SULFONAMIDES AND PHENOLIC COMPONENTS; EXPOSING TO LIGHT FUJI PHOTO FILM CO., LTD. (JP) 1990-05-29 US disclosed
US-4824721-A CAPSULES OF OIL SOLUBLE DYES WHICH SWELL AND RELEASE DYE UPON HEATING FUJI PHOTO FILM CO., LTD. (JP) 1989-04-25 US disclosed
US-4758495-A Diazo microcapsule recording material prepared using ion exchange treatment FUJI PHOTO FILM CO., LTD. (JP) 1988-07-19 US disclosed
US-4749679-A Heat sensitive recording materials FUJI PHOTO FILM CO., LTD. (JP) 1988-06-07 US disclosed
EP-0262953-A2 Heat-sensitive recording material FUJI PHOTO FILM CO., LTD. (JP) 1988-04-06 EP disclosed
US-4682194-A MICROCAPSULES CONTAINING LEUCO DYE FUJI PHOTO FILM CO., LTD. (JP) 1987-07-21 US disclosed
US-4644376-A Heat-sensitive recording material FUJI PHOTO FILM CO., LTD. (JP) 1987-02-17 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10301258-B2 Benzende sulfonamide derivatives as HIV integrase inhibitors NR2E3, NR2E1, PIM3 ALDH1A1 2073/4885CA12 3817/4885CA2 2857/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.