Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8990426 | 0.90 | LTB4R (1.00) | LTB4RLTB4R2 | |
| SCHEMBL9198551 | 0.89 | LTB4R (0.84) | LTB4RLTB4R2 | |
| SCHEMBL9198567 | 0.80 | LTB4R (0.82) | LTB4RLTB4R2 | |
| SCHEMBL8990528 | 0.80 | LTB4R (1.00) | LTB4RLTB4R2 | |
| SCHEMBL9192574 | 0.78 | LTB4R (0.88) | LTB4RLTB4R2 | |
| SCHEMBL8990523 | 0.76 | LTB4R (0.77) | LTB4RLTB4R2 | |
| SCHEMBL9779682 | 0.76 | LTB4R (0.77) | LTB4RLTB4R2 | |
| SCHEMBL9196388 | 0.76 | LTB4R (0.81) | LTB4RLTB4R2 | |
| SCHEMBL9201146 | 0.76 | LTB4R (0.81) | LTB4RLTB4R2 | |
| SCHEMBL9199443 | 0.76 | LTB4R (0.64) | LTB4RLTB4R2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6617345-B1 | Cyclooxygenase-2 inhibitor is (5-bromo-2-(4-fluorophenyl )-3-(4-(methylsulfonyl)phey)-thiophene), N-(2-(cyclohexyloxy 4-nitrophenyl)-methanesulfonamide), meloxicam, flosulide or cyclic substituted phenyl sulfones or sulfonamides | G.D. SEARLE & CO. | 2003-09-09 | — | — | US | disclosed |