SCHEMBL720119

SCHEMBL720119

Nc1cccc(CO)c1N

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 4/20 0.43
TSHR P16473 4/20 0.43
ALDH1A1 P00352 3/20 0.43
HPGD P15428 2/20 0.43
HSD17B10 Q99714 2/20 0.43
TDP1 Q9NUW8 1/20 0.43
CD44 P16070 1/20 0.42
APOBEC3G Q9HC16 1/20 0.39
CHRNE Q04844 1/20 0.39
PDCD1 Q15116 1/20 0.38
CD274 Q9NZQ7 1/20 0.38
KEAP1 Q14145 1/20 0.37
ALOX15 P16050 2/20 0.36
CASP1 P29466 1/20 0.36
CASP7 P55210 1/20 0.36
SMN1; SMN2 Q16637 1/20 0.36
PIK3CA P42336 1/20 0.36
NR4A2 P43354 1/20 0.34
FDPS P14324 1/20 0.34
PDK2 Q15119 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15390567 0.87 APOBEC3G (0.44) CYP3A4TSHRALDH1A1HPGDHSD17B10
SCHEMBL30645118 0.81 CD44 (0.39) CYP3A4TSHRALDH1A1HPGDHSD17B10
SCHEMBL992770 0.81 CD44 (0.39) CYP3A4TSHRALDH1A1HPGDHSD17B10
SCHEMBL3786241 0.81 ALDH1A1 (0.52) CYP3A4TSHRALDH1A1HPGDHSD17B10
SCHEMBL6938421 0.80 CYP3A4 (0.43) CYP3A4TSHRALDH1A1HPGDHSD17B10
SCHEMBL3132841 0.79 CD44 (0.46) CYP3A4TSHRALDH1A1HPGDHSD17B10
SCHEMBL3482721 0.79 CD44 (0.46) CYP3A4TSHRALDH1A1HPGDHSD17B10
Isatoic Anhydride SCHEMBL16252 0.79
Isatoic Anhydride SCHEMBL29700086 0.79
SCHEMBL2123567 0.78 CYP3A4 (0.42) CYP3A4TSHRALDH1A1HPGDHSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 130 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111499901-B Preparation method of fluorine-containing polymer/polyimide composite film 东莞东阳光科研发有限公司 2022-07-08 CN claimed
CN-111499901-A Preparation method of fluorine-containing polymer/polyimide composite film 东莞东阳光科研发有限公司 2020-08-07 CN claimed
WO-2004078118-A2 PROTEIN KINASE C INHIBITOR, RELATED COMPOSITION, AND METHOD OF USE THE GOVERNMENT OF THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) 2004-09-16 WO claimed
JP-3008195-B2 2000-02-14 JP claimed
US-5891870-A ANTIINFLAMMATORY AGENTS USING BENZODITERPENES AND BENZOLACTAMS PROCYON PHARMACEUTICALS, INC. (US) 1999-04-06 US claimed
US-5716968-A ANTIINFLAMMATORY AGENTS; VIRICIDE PROCYON PHARMACEUTICALS, INC. (US) 1998-02-10 US claimed
EP-0310622-A1 ANTI-INFLAMMATORY COMPOSITIONS. ALDER RES CENTER CORP (US) 1989-04-12 EP claimed
WO-1987007599-A2 ANTI-INFLAMMATORY COMPOSITIONS ALDER RESEARCH CENTER CORPORATION (US) 1987-12-17 WO claimed
JP-62100530-A None JP disclosed
WO-2024153077-A1 HPK1 INHIBITOR, AND PREPARATION METHOD THEREFOR AND USE THEREOF 中国科学院上海有机化学研究所 2024-07-25 WO disclosed
CN-118344358-A HPK1 inhibitor and preparation method and application thereof 中国科学院上海有机化学研究所 2024-07-16 CN disclosed
CN-111344281-B Potassium channel inhibitors substituted benzimidazoles 阿塞西翁制药公司 2023-11-14 CN disclosed
CN-111372928-B Benzimidazole derivatives as potassium channel inhibitors 阿塞西翁制药公司 2023-05-16 CN disclosed
CN-111499901-B Preparation method of fluorine-containing polymer/polyimide composite film 东莞东阳光科研发有限公司 2022-07-08 CN disclosed
EP-0310622-B1 ANTI-INFLAMMATORY COMPOSITIONS ALDER RESEARCH CENTER LIMITED PARTNERSHIP (US) 1992-04-15 EP disclosed
WO-1992002484-A1 PROTEIN KINASE C MODULATORS WITH ANTI-INFLAMMATORY AND ANTIVIRAL ACTIVITY ALDER RESEARCH CENTER LIMITED PARTNERSHIP (US) 1992-02-20 WO disclosed
EP-0455271-A2 Anti-inflammatory compositions PROCYON PHARMACEUTICALS, INC. (US) 1991-11-06 EP disclosed
EP-0310622-A1 ANTI-INFLAMMATORY COMPOSITIONS. ALDER RES CENTER CORP (US) 1989-04-12 EP disclosed
WO-1987007599-A2 ANTI-INFLAMMATORY COMPOSITIONS ALDER RESEARCH CENTER CORPORATION (US) 1987-12-17 WO disclosed
JP-S62100530-A SOLUBLE AROMATIC POLYIMIDE COMPOSITION UBE IND LTD 1987-05-11 JP disclosed